5988-19-2 Usage
Chemical Properties
White to off-white crystalline powder
Uses
L-Dihydroorotic acid a metabolite.
Biochem/physiol Actions
L-Dihydroorotic acid (DHO) serves as a substrate for dihydroorotate dehydrogenase (DHODH), an enzyme in the de novo synthesis of pyrimidine. Inhibition of DHOH by its inhibitors causes a large accumulation of upstream metabolite DHO and a reduction in the uridine levels. Therefore, DHO and uridine can be used as biomarkers for pyrimidine synthesis for the clinical development of DHOH inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 5988-19-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5988-19:
(6*5)+(5*9)+(4*8)+(3*8)+(2*1)+(1*9)=142
142 % 10 = 2
So 5988-19-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m0/s1
