58849-84-6

Basic information

• Product Name: 3-Methyl-2-[3-oxo-4-(2-phenoxy-acetylamino)-3H-isothiazol-2-yl]-but-2-enoic acid 2,2,2-trichloro-ethyl ester
• CAS NO: 58849-84-6
• Molecular Weight: 479.768
• Mol File: 58849-84-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Methyl-2-[3-oxo-4-(2-phenoxy-acetylamino)-3H-isothiazol-2-yl]-but-2-enoic acid 2,2,2-trichloro-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-2-[3-oxo-4-(2-phenoxy-acetylamino)-3H-isothiazol-2-yl]-but-2-enoic acid 2,2,2-trichloro-ethyl ester(58849-84-6)
• EPA Substance Registry System: 3-Methyl-2-[3-oxo-4-(2-phenoxy-acetylamino)-3H-isothiazol-2-yl]-but-2-enoic acid 2,2,2-trichloro-ethyl ester(58849-84-6)

Safety Data

• Hazardous Substances Data: 58849-84-6(Hazardous Substances Data)

Upstream product

• 19474-21-6 trichloroethyl 6β-phenoxyacetamidopenicillanate-1β-sulfoxide 
• 106-45-6 para-thiocresol 
• 106-54-7 p-Chlorothiophenol 
• 19474-21-6 trichloroethyl ester of 6-phenoxyacetamido penicillinate sulfoxide 
• 623-51-8 ethyl 2-sulfanylacetate 
• 108-98-5 thiophenol 
• 696-63-9 4-Methoxybenzenethiol 
• 1445-45-0 Trimethyl orthoacetate 

Relevant articles and documents

THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. ARYL MERCAPTANS

Aryl mercaptans, unlike heterocyclic mercaptans, reacted exceptionally slowly with penicillin sulfoxides.These reactions are affected by the substituent at the C-6 position of the penam, and by the nature of the ester group at the C-3 position.The unsym- azetidinone disulfides obtained from these reactions, unlike those from heterocyclic mercaptans, did not react with halogenating agents such as cupric chloride.

PENICILLIN SULFOXIDE THERMOLYSIS IN TRIMETHYL ORTHOACETATE

The thermolysis of trichloroethyl 6-phenoxyacetamidopenicillanate sulfoxide in trimethyl orthoacetate gave four -lactam cleaved products.