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58534-46-6

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58534-46-6 Usage

Description

(Z)-Desmethyldoxepin, also known as desmethyldoxepin, is a chemical compound derived from the tricyclic antidepressant doxepin. It functions as a selective antagonist of the histamine H1 receptor and is recognized for its significant sedative effects. (Z)-Desmethyldoxepin has demonstrated therapeutic potential in treating various conditions due to its ability to reduce itching, promote sleep, and manage anxiety-related disorders.

Uses

Used in Pharmaceutical Industry:
(Z)-Desmethyldoxepin is used as an antipruritic agent for the treatment of conditions such as pruritus, urticaria, and atopic dermatitis. Its effectiveness in reducing itching and promoting sleep makes it a valuable compound in this application.
Used in Sleep Aid Applications:
(Z)-Desmethyldoxepin is used as a sedative to help manage insomnia due to its sleep-promoting properties. Its sedative effects contribute to its potential as a treatment for individuals struggling with sleep disorders.
Used in Anxiety Management:
(Z)-Desmethyldoxepin is used as a potential treatment for anxiety-related disorders. Its ability to manage anxiety makes it a compound of interest in the development of therapeutic strategies for anxiety management.
Overall, (Z)-Desmethyldoxepin is a pharmacologically active compound with diverse applications in the treatment of various conditions, particularly in the pharmaceutical and healthcare industries.

Check Digit Verification of cas no

The CAS Registry Mumber 58534-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,3 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 58534-46:
(7*5)+(6*8)+(5*5)+(4*3)+(3*4)+(2*4)+(1*6)=146
146 % 10 = 6
So 58534-46-6 is a valid CAS Registry Number.

58534-46-6Downstream Products

58534-46-6Relevant articles and documents

N-DESMETHYL-DOXEPIN AND METHODS OF USING THE SAME TO TREAT SLEEP DISORDERS

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Page/Page column 19-20, (2010/11/29)

The invention relates to desmethyldoxepin, isomers of desmethyldoxepin, and pharmaceutically acceptable salts and prodrugs of desmethyldoxepin; compositions containing the same, and the use of any of the aforementioned for the treatment of sleep disorders.

EFFICIENT SYNTHESIS OF TRICYCLIC ANTIDEPRESSANT NORMETABOLITES

Adamczyk, Maciek,Fishpaugh, Jeffrey R.,Johnson, Donald

, p. 168 - 171 (2007/10/03)

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