584-82-7

Basic information

• Product Name: 2-ALLYL-4-METHOXYPHENOL
• Synonyms: 2-(2-Propenyl)-4-methoxyphenol;4-Methoxy-2-allylphenol;Nsc404069;Phenol, 2-allyl-4-methoxy-;Phenol, 4-methoxy-2-(2-propenyl)-;Wln: 1U2R bq eo1;4-methoxy-2-(prop-2-en-1-yl)phenol
• CAS NO: 584-82-7
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 584-82-7.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 274.8°C at 760 mmHg
• Flash Point: 133.2°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 0.00315mmHg at 25°C
• Refractive Index: 1.535
• PKA: 10.78±0.18(Predicted)
• CAS DataBase Reference: 2-ALLYL-4-METHOXYPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ALLYL-4-METHOXYPHENOL(584-82-7)
• EPA Substance Registry System: 2-ALLYL-4-METHOXYPHENOL(584-82-7)

Safety Data

• Hazardous Substances Data: 584-82-7(Hazardous Substances Data)

Usage

Chemical compound

2-ALLYL-4-METHOXYPHENOL

Physical appearance

Pale yellow, oily liquid

Aroma

Pleasant, spicy

Found in

Essential oils such as clove oil, nutmeg, and cinnamon

Applications

Flavoring agent in food and beverages
Fragrance in perfumes and cosmetics
Topical analgesic and antiseptic in medicine

Properties

Antioxidant
Anti-inflammatory
Antimicrobial

Use in

Pharmaceuticals
Personal care products

Other uses

Synthesis of other chemicals
Fumigant to control pests in agriculture

Caution

Can cause skin and respiratory irritations in high concentrations

InChI:InChI=1/C10H12O2/c1-3-4-8-7-9(12-2)5-6-10(8)11/h3,5-7,11H,1,4H2,2H3

Upstream product

• 111-90-0 ethoxyethoxyethanol 
• 13391-35-0 allyl (4-methoxyphenyl) ether 
• 121-69-7 N,N-dimethyl-aniline 
• 4873-09-0 allyl tosylate 
• 150-76-5 4-methoxy-phenol 
• 1746-13-0 allyl phenyl ether 
• 106-95-6 allyl bromide 
• 123-31-9 hydroquinone 
• 37592-19-1 3-allyloxyanisole 
• 959697-71-3 2-allyl-4-methoxy-1-prop-2-ynyloxy-benzene 
• 101-84-8 diphenylether 

Downstream Products

• 100117-70-2 2-allyl-4-methoxyphenyl acetate 
• 205433-77-8 2-allyl-1-allyloxy-4-methoxy-benzene 
• 126708-03-0 2-<2-hydroxy-3-(phenylthio)propyl>-4-methoxyphenol 
• 126708-12-1 2-<3-hydroxy-2-(phenylthio)propyl>-4-methoxyphenol 
• 101041-33-2 5-methoxy-2-(phenylthiomethyl)-2,3-dihydrobenzofuran 
• 18385-84-7 6-methoxy-2H-chromene 
• 205433-71-2 2-allyl-4,4-dimethoxy-2,5-cyclohexadienone 
• 13391-31-6 4-methoxy-2-propylphenol 
• 272125-01-6 2-(5-chloro-4,4,5,5-tetrafluoro-2-iodo-pentyl)-4-methoxy-phenol 
• 736985-50-5 2-allyl-1-(tert-butyldimethylsilyloxy)-4-methoxybenzene 
• 634153-26-7 2-allyl-4-methoxy-1-(methoxymethoxy)benzene 
• 959697-71-3 2-allyl-4-methoxy-1-prop-2-ynyloxy-benzene 
• 3731-95-1 2-allyl-1,4-benzoquinone 
• 205433-74-5 2-allyl-1-(benzyloxy)-4-methoxybenzene 

Relevant articles and documents

Allylphenols as a new class of human 15-lipoxygenase-1 inhibitors

In this study, a series of mono- and diallylphenol derivative were designed, synthesized, and evaluated as potential human 15-lipoxygenase-1 (15-hLOX-1) inhibitors. Radical scavenging potency of the synthetic allylphenol derivatives was assessed and the results were in accordance with lipoxygenase (LOX) inhibition potency. It was found that the electronic natures of allyl moiety and para substituents play the main role in radical scavenging activity and subsequently LOX inhibition potency of the synthetic inhibitors. Among the synthetic compounds, 2,6-diallyl-4-(hexyloxy)phenol (42) and 2,6-diallyl-4-aminophenol (47) showed the best results for LOX inhibition (IC50 = 0.88 and 0.80 μM, respectively).

TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND

Disclosed are a series of tricyclic furan-substituted piperidinedione compounds and an application thereof in preparing a drug for treating a disease related to CRBN protein. In particular, disclosed is a derivative compound represented by formula (I) or a pharmaceutically acceptable salt thereof.

Total Synthesis of Pyrolaside B: Phenol Trimerization through Sequenced Oxidative C?C and C?O Coupling

A facile method to oxidatively trimerize phenols using a catalytic aerobic copper system is described. The mechanism of this transformation was probed, yielding insight that enabled cross-coupling trimerizations. With this method, the natural product pyro