583037-96-1

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-8-(3-methyl-2-butenyl)-
• CAS NO: 583037-96-1
• Molecular Formula: C24H22O7
• Molecular Weight: 422.434
• Mol File: 583037-96-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-8-(3-methyl-2-butenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-8-(3-methyl-2-butenyl)-(583037-96-1)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-8-(3-methyl-2-butenyl)-(583037-96-1)

Safety Data

• Hazardous Substances Data: 583037-96-1(Hazardous Substances Data)

Upstream product

• 65388-04-7 4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate 
• 583037-95-0 4-(7-acetyloxy-5-((3-methylbut-2-en-l-yl))-4-oxo-4H-chromen-3-yl)phenyl acetate 

Downstream Products

• 104691-86-3 lupiwighteone 

Relevant articles and documents

Induction of enantio-selective apoptosis in human leukemia HL-60 cells by (S)-erypoegin K, an isoflavone isolated from Erythrina poeppigiana

Erypoegin K, an isoflavone isolated from the stem bark of Erythrina poeppigiana, has potent apoptosis-inducing effect on human leukemia HL-60 cells. Erypoegin K has a chiral carbon at the C-2′′ position of its furan ring and naturally occurs as a racemic mixture of (S)- and (R)-isomers. In the present study, we semi-synthesized (RS)-erypoegin K from genistein and separated the optical isomers by HPLC using a chiral column to characterize its apoptosis-inducing activity. Apoptotic cell death was assessed by analyzing caspase-3 and caspase-9 activation, nuclear fragmentation, and genomic DNA ladder formation. (S)-erypoegin K showed exclusive anti-proliferative and apoptosis-inducing activity, with an IC50 value of 90 nM, about 50% lower than that of its racemic mixture (175 nM). By contrast, no apoptosis-inducing activity was shown by the (R)-isomer. In addition, methylglyoxal accumulation in the culture medium was observed only in cells treated with (S)-erypoegin K. These results demonstrated that (S)-erypoegin K is a unique bioactive component that has potent apoptosis-inducing activity on HL-60 cells.

Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

A new isoflavonoid, 5-hydroxy-3-(4-hydroxyphenyl)-8-isopropenyl-8,9- dihydro-4H-furo-[2,3-h]-chromen-4-one named derrisisoflavone G (1), four known prenylated flavanones (2-5), four known isoflavonoids (6-9) and two phenolic derivatives (10, 11) have been

Synthesis of lupiwighteone via a para-Claisen-Cope rearrangement

The lanthanide catalysed para-Claisen-Cope rearrangement has been used as the key step in a short synthesis of the prenylated isoflavone, lupiwighteone. The Mitsunobu reaction was employed for the 5-O-prenylation of the acid/base sensitive acetylated isof