57999-08-3 Usage
Description
4-(4-bromophenyl)-1H-pyrazol-5-amine is a chemical compound belonging to the pyrazole class of organic compounds, characterized by a pyrazole ring with a 4-(4-bromophenyl) substituent. It has the molecular formula C9H8BrN3 and is recognized for its potential as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
4-(4-bromophenyl)-1H-pyrazol-5-amine is used as a chemical intermediate for the development of new drugs targeting various medical conditions. Its unique structure allows for the creation of novel therapeutic agents that can address unmet medical needs.
Used in Agricultural Industry:
In the agricultural sector, 4-(4-bromophenyl)-1H-pyrazol-5-amine is utilized in the production of herbicides and pesticides. Its application contributes to the development of effective crop protection solutions, enhancing agricultural productivity and crop quality.
Check Digit Verification of cas no
The CAS Registry Mumber 57999-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,9 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 57999-08:
(7*5)+(6*7)+(5*9)+(4*9)+(3*9)+(2*0)+(1*8)=193
193 % 10 = 3
So 57999-08-3 is a valid CAS Registry Number.
57999-08-3Relevant articles and documents
Novel tricyclic pyrazolopyrimidines as potent and selective GPR119 agonists
Azimioara, Mihai,Alper, Phil,Cow, Christopher,Mutnick, Daniel,Nikulin, Victor,Lelais, Gerald,Mecom, John,McNeill, Matthew,Michellys, Pierre-Yves,Wang, Zhiliang,Reding, Esther,Paliotti, Michael,Li, Jing,Bao, Dingjiu,Zoll, Jocelyn,Kim, Young,Zimmerman, Matthew,Groessl, Todd,Tuntland, Tove,Joseph, Sean B.,McNamara, Peter,Seidel, H. Martin,Epple, Robert
supporting information, p. 5478 - 5483 (2015/01/09)
Systematic SAR optimization of the GPR119 agonist lead 1, derived from an internal HTS campaign, led to compound 29. Compound 29 displays significantly improved in vitro activity and oral exposure, leading to GLP1 elevation in acutely dosed mice and reduc