57956-39-5Relevant articles and documents
Photoaddition reactions of acetylpyridines with silyl ketene acetals: SET vs [2 + 2]-cycloaddition pathways
Cho, Dae Won,Park, Hea Jung,Yoon, Ung Chan,Lee, Hyang-Yeol,Mariano, Patrick S.
, p. 10304 - 10313 (2013/01/15)
Photoaddition reactions of silyl ketene acetals with 2-, 3- and 4-acetylpyridine have been explored. The results show that the acetylpyridines react with an electron rich, dimethyl-substituted silyl ketene acetal via a pathway in which excited state singl
Catalytic enantioselective intermolecular reductive aldol reaction to ketones
Zhao, Dongbo,Oisaki, Kounosuke,Kanai, Motomu,Shibasaki, Masakatsu
, p. 1403 - 1407 (2007/10/03)
We describe the first example of a catalytic enantioselective intermolecular reductive aldol reaction. Three types of reactions were studied: (1) reactions between acetophenone and methyl acrylate; (2) reactions between symmetric ketones and β-substituted
A new method for the catalytic aldol reaction to ketones
Oisaki, Kounosuke,Suto, Yutaka,Kanai, Motomu,Shibasaki, Masakatsu
, p. 5644 - 5645 (2007/10/03)
A new method for the catalytic aldol reaction to ketones, using CuF·3PPh3·2EtOH complex as the catalyst and (EtO)3SiF as the additive, is described. The reaction can be applied to a wide range of ketones and trimethylsilyl enolates. On the basis of mechanistic studies, a working hypothesis for the catalytic cycle is proposed, in which the dynamic ligand exchange mediated by copper silicates produces the active copper enolate. Moreover, the present reaction can be extended to the catalytic enantioselective reaction using tol-BINAP as a chiral ligand. Copyright
