5779-93-1Relevant articles and documents
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Chollet,A. et al.
, p. 511 - 524 (1979)
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A NOVEL ROUTE FOR PREPARATION OF L,3:2,4-BIS-(3,4- D IM ETH YLB ENZYLIDENE)SO RB ITO L
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Page/Page column 6; 7, (2016/06/01)
A new route for preparation of 3:2,4-bis-(3,4- dimethylbenzylidene) sorbitol [DMDBS] has been disclosed which is comprising: bromination of o-xylene to obtain a mixture of 4-bromo- o-xylene as a major product and 3-bromo-o-xylene; conversion of bromo-o-xylenes into corresponding dimethylbenzaldehyde by Grignard reaction; and reaction of 3,4-dimethylbenzaldehyde with sorbitol in presence of catalyst and solvent to obtain DMDBS. The invented route is cost-effective and it obviates the need to separate 3,4-dimethylbenzaldehyde from its 2,3-isomer.
Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl4: Scope and limitations
Ramos-Tomillero, Iván,Paradís-Bas, Marta,De Pinho Ribeiro Moreira, Ibério,Bofill, Josep María,Nicolás, Ernesto,Albericio, Fernando
supporting information, p. 5409 - 5422 (2015/05/13)
Here the aromatic formylation mediated by TiCl4 and dichloromethyl methyl ether previously described by our group has been explored for a wide range of aromatic rings, including phenols, methoxy- and methylbenzenes, as an excellent way to produce aromatic aldehydes. Here we determine that the regioselectivity of this process is highly promoted by the coordination between the atoms present in the aromatic moiety and those in the metal core.