57625-28-2

Basic information

• Product Name: 2-Propenamide, N,N-bis(phenylmethyl)-
• CAS NO: 57625-28-2
• Molecular Formula: C17H17NO
• Molecular Weight: 251.328
• Mol File: 57625-28-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, N,N-bis(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, N,N-bis(phenylmethyl)-(57625-28-2)
• EPA Substance Registry System: 2-Propenamide, N,N-bis(phenylmethyl)-(57625-28-2)

Safety Data

• Hazardous Substances Data: 57625-28-2(Hazardous Substances Data)

Usage

General Description

2-Propenamide, N,N-bis(phenylmethyl)-, also known as N,N'-methylenebisacrylamide, is a chemical compound commonly used in various industries including cosmetics, adhesives, and pharmaceuticals. It is a colorless crystalline solid with a faint odor, and it is highly soluble in water. N,N'-methylenebisacrylamide is primarily used as a cross-linking agent in the production of polymers and gels, as it helps to form strong and durable bonds between polymer chains. It is also utilized in the manufacturing of contact lenses, dental materials, and tissue adhesives. However, it is important to handle this chemical with care, as it can be an irritant to the skin, eyes, and respiratory tract, and is considered to be a potential human carcinogen.

Upstream product

• 79-10-7 acrylic acid 
• 103-49-1 dibenzylamine 
• 814-68-6 acryloyl chloride 
• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 
• 110-91-8 morpholine 
• 110-89-4 piperidine 
• 147-85-3 L-proline 
• 123-75-1 pyrrolidine 

Downstream Products

• 183207-21-8 N,N-Dibenzyl-3-(1-hydroxy-cyclohexyl)-propionamide 
• 1510826-46-6 2-(9-(2-chlorobenzyl)-9H-purin-6-yl)-N,N-dibenzyl-4-phenylbutanamide 
• 1510826-45-5 N,N-dibenzyl-2-(9-phenethyl-9H-purin-6-yl)-4-phenylbutanamide 
• 1510826-44-4 N,N-dibenzyl-2-(9-cyclopentyl-9H-purin-6-yl)-4-phenylbutanamide 
• 1510826-43-3 N,N-dibenzyl-2-(9-butyl-9H-purin-6-yl)-4-phenylbutanamide 
• 1510826-42-2 N,N-Dibenzyl-2-(9-ethyl-9H-purin-6-yl)-4-phenylbutanamide 
• 1510826-41-1 N,N-dibenzyl-2-(9-methyl-9H-purin-6-yl)-4-phenylbutanamide 
• 1510826-52-4 N,N-dibenzyl-2-(9-benzyl-9H-purin-6-yl)-4-(4-(trifluoromethyl)phenyl)butanamide 
• 1510826-51-3 N,N-dibenzyl-2-(9-benzyl-9H-purin-6-yl)-4-(3-chlorophenyl)butanamide 

Relevant articles and documents

Adhesive composition

PROBLEM TO BE SOLVED: To provide an adhesive composition having excellent adhesion to a cycloolefin resin or the like. SOLUTION: An adhesive composition of the present invention comprises a polymer having a repeating unit derived from a polymerizable comp

Potassium Base-Catalyzed Michael Additions of Allylic Alcohols to α,β-Unsaturated Amides: Scope and Mechanistic Insights

We report herein the first KHMDS-catalyzed Michael additions of allylic alcohols to α,β-unsaturated amides through allylic isomerization. The reaction proceeds smoothly in the presence of only 5 mol% of KHMDS to afford a variety of 1,5-ketoamides in high yields. Mechanistic investigations, including experimental and computational studies, reveal that the KHMDS-catalyzed in-situ generation of the enolate from the allylic alcohol through a tunneling-assisted 1,2-hydride shift is the key to the success of this transformation. (Figure presented.).

Synthesis of Acrylamides via the Doebner-Knoevenagel Condensation

A selective synthesis of acrylamides had been developed using the Doebner-Knoevenagel condensation. The reaction occurs under mild conditions at ambient temperatures, tolerates a wide array of functional groups, and affords the E-isomer with high selectivity. The reported method expands the scope of this classic reaction to a class of industrially important products and as well as to the use of aliphatic aldehydes. An organocatalytic mechanism has been proposed, and the ability to scale the process has been demonstrated.