575452-22-1

Basic information

• Product Name: 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole
• Synonyms: 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole;1-(1-Ethoxyethyl)-4-iodopyrazole;1H-Pyrazole, 1-(1-ethoxyethyl)-4-iodo-
• CAS NO: 575452-22-1
• Molecular Formula: C₇H₁₁IN₂O
• Molecular Weight: 266.07951
• Mol File: 575452-22-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 74-76 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.72±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0.19±0.10(Predicted)
• CAS DataBase Reference: 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole(575452-22-1)
• EPA Substance Registry System: 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole(575452-22-1)

Safety Data

• Hazardous Substances Data: 575452-22-1(Hazardous Substances Data)

Usage

General Description

1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole is a chemical compound with the molecular formula C7H11IN2O. It is a pyrazole derivative with an ethoxyethyl group attached to the nitrogen atom and an iodine atom at the 4-position on the pyrazole ring. 1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole is often used in research and pharmaceutical applications for its potential biological activity and pharmacological properties. Its synthesis and study have been of interest due to its potential applications in the development of new drugs and biologically active compounds. Additionally, the compound's structure and properties make it a valuable tool for studying the reactivity and behavior of pyrazole derivatives in organic chemistry and biochemistry.

Upstream product

• 3469-69-0 4-iodopyrazole 
• 109-92-2 ethyl vinyl ether 

Downstream Products

• 1002535-21-8 3-(1-H-pyrazole-4-yl)benzoic acid 
• 1037785-41-3 4-((E)-2-(1-(1-Ethoxyethyl)-1H-pyrazol-4-yl) vinyl)benzonitrile 
• 1029716-44-6 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 
• 1017794-47-6 4-(1H-pyrazol-4-yl)benzoic acid 
• 10199-68-5 4-phenyl-1H-pyrazole 
• 815608-06-1 1-(1-ethoxyethyl)-1H-pyrazole-4-carbaldehyde 
• 28791-95-9 1-(1-ethoxyethyl)-1H-pyrazole 

Relevant articles and documents

4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS

Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3 and R4 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase-associated diseases and disorders, such as autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.

Highly hydrophobic isoreticular porous metal-organic frameworks for the capture of harmful volatile organic compounds

Tunable hydrophobicity: Efficient air filters for the protection against chemical warfare agents might be achieved by surface functionalization of the pores in robust metal-organic frameworks (MOFs) with fluoroalkyl residues and the precise control of their pore size (see picture). These MOFs capture harmful volatile organic compounds even under extremely moist conditions (80 % relative humidity). Copyright

PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS

The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.