5700-04-9 Usage
Description
1,3-DIAZEPANE-2-THIONE, also known as Diap, is a heterocyclic compound with a seven-membered ring containing two nitrogen atoms and a sulfur atom. It is a key intermediate in the synthesis of various organic and inorganic compounds, particularly in the development of pharmaceuticals and coordination complexes.
Source:
1,3-DIAZEPANE-2-THIONE can be synthesized through various methods, including the reaction of 1,3-dichloropropan-2-ol with thiourea or the cyclization of 1,3-diaminopropan-2-ol with carbon disulfide.
Production Methods:
The synthesis of 1,3-DIAZEPANE-2-THIONE typically involves the cyclization of 1,3-diaminopropan-2-ol with carbon disulfide, followed by subsequent reactions to introduce the desired functional groups or substituents.
Uses
Used in Pharmaceutical Industry:
1,3-DIAZEPANE-2-THIONE is used as a key intermediate in the synthesis of various pharmaceutical compounds, such as benzodiazepines, which are widely used as anxiolytics, sedatives, and hypnotics. Its unique structure allows for the development of new drugs with improved pharmacological properties and reduced side effects.
Used in Coordination Chemistry:
1,3-DIAZEPANE-2-THIONE is used as a ligand in the synthesis of coordination complexes, such as cadmium chloride complexes (e.g., Cd(Diap)2Cl2). These complexes exhibit substantial antibacterial activities, making them potential candidates for the development of new antimicrobial agents to combat drug-resistant bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 5700-04-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,0 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5700-04:
(6*5)+(5*7)+(4*0)+(3*0)+(2*0)+(1*4)=69
69 % 10 = 9
So 5700-04-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2S/c8-5-6-3-1-2-4-7-5/h1-4H2,(H2,6,7,8)
5700-04-9Relevant articles and documents
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
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Paragraph 00711, (2021/11/26)
The present disclosure provides modified oligonucleotides and compositions and methods thereof. In some embodiments, provided technologies comprise modified sugars and/or modified internucleotidic linkages. In some embodiments, the present disclosure provides technologies for preparing modified oligonucleotides. In some embodiments, the present disclosure provides chirally controlled oligonucleotide compositions and methods for their preparation and uses.
Bis-(triethylphosphine)platinum(II) complexes with thiones as anti cancer agents
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Page/Page column 20, (2017/02/28)
Platinum(II) complexes having mixed ligands as anticancer agents. The central platinum atom is coordinated by two phosphine ligands and two heterocyclic thione ligands. Each heterocyclic thione ligand has a five-, six- or seven-membered heterocyclic ring with two nitrogen atoms at positions 1 and 3 of the ring and a thiocarbonyl group at position 2. Pharmaceutical compositions incorporated the platinum(II) complexes, methods of synthesizing the complexes and methods of treating cancers with the complexes or pharmaceutical compositions thereof are also described.
Platinum(II) complexes with thione ligands and methods thereof
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Page/Page column 20, (2016/11/21)
Platinum(II) complexes having thione-based heterocyclic ligands as anticancer agents. The central platinum atom is coordinated by four of the ligands, each having a five-, six- or seven-membered heterocyclic ring with two nitrogen atoms at positions 1 and 3 of the ring and a thiocarbonyl group at position 2. Pharmaceutical compositions incorporated the platinum(II) complexes, methods of synthesizing the complexes and methods of treating cancers with the complexes or pharmaceutical compositions thereof are also described.
