56977-92-5 Usage
Description
(R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE, also known as (R,R)-(-)-1,2-Ethanediylbis[(2-methoxyphenyl)phenylphosphine]rhodium(I) Tetrafluoroborate, is an organorhodium compound that exists as an orange crystalline powder. It is characterized by its unique chemical structure, which features a rhodium atom bonded to two phosphine ligands and a 1,5-cyclooctadiene group. (R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is known for its catalytic properties in various chemical reactions.
Uses
Used in Pharmaceutical Industry:
(R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is used as a catalyst for the synthesis of Sinefungin (S487100), a natural nucleoside analog of S-adenosylmethionine. Sinefungin plays a crucial role in inhibiting Streptococcus pneumoniae biofilm growth, which is essential for the development of new antibiotics and treatments for bacterial infections.
Used in Biochemical Research:
In the field of biochemical research, (R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE serves as a catalyst for the synthesis of derivatives that can be used as inhibitors and structure probes for human protein lysine methyltransferase SETD2. This application is vital for understanding the role of protein methylation in various cellular processes and the development of targeted therapies for diseases associated with aberrant methylation.
Chemical Properties:
(R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is an orange crystalline powder with unique chemical properties that make it an effective catalyst in various chemical reactions, particularly in the synthesis of biologically active compounds and pharmaceuticals.
Reaction
Highly reactive enantioselective catalyst for the asymmetric hydrogenation of various substituted dehydroalanines to Nprotected aminoacids. Also, catalyst is very effective in the asymmetric reduction of pentapetides that contain unsaturated Phe or Tyr linkages to enkephalin, a brain peptide hormone.
Efficient catalyst for the asymmetric reduction of enol acetates to esters.
Catalyst used to prepare chiral 2-substituted succinic acid derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 56977-92-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,9,7 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 56977-92:
(7*5)+(6*6)+(5*9)+(4*7)+(3*7)+(2*9)+(1*2)=185
185 % 10 = 5
So 56977-92-5 is a valid CAS Registry Number.