56776-01-3 Usage
Description
Tulobuterol hydrochloride is a hydrochloride salt of Tulobuterol, a sympathomimetic drug that functions as a β-adrenergic receptor agonist. Structurally related to Terbutaline, it is used to increase normal diaphragm muscle strength and is commonly administered through a transdermal patch.
Uses
Used in Pharmaceutical Industry:
Tulobuterol hydrochloride is used as a therapeutic agent for respiratory conditions, specifically to enhance diaphragm muscle strength. It acts as a β-adrenergic receptor agonist, helping to improve breathing efficiency in patients with respiratory issues.
Used in Transdermal Patch Formulation:
Tulobuterol hydrochloride is utilized as an active ingredient in transdermal patches, allowing for controlled and sustained drug delivery. This method of administration ensures that the medication is consistently absorbed into the bloodstream, providing a maintained therapeutic effect over an extended period.
Check Digit Verification of cas no
The CAS Registry Mumber 56776-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,7,7 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56776-01:
(7*5)+(6*6)+(5*7)+(4*7)+(3*6)+(2*0)+(1*1)=153
153 % 10 = 3
So 56776-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H/t11-;/m0./s1
56776-01-3Relevant articles and documents
Synthesis of the β2-Agonist Tulobuterol and Its Metabolite 4-Hydroxytulobuterol
Burdeinyi, M. L.,Glushkova, M. A.,Popkov, S. V.
, p. 390 - 394 (2020/04/27)
Abstract: Alternative methods have been developed for the synthesis of theβ2-agonist tulobuterol and its metabolite4-hydroxytulobuterol with a similar activity. The proposed procedures utilizeavailable reagents, and the key stage in the synthesis is the formation ofintermediate oxirane according to the Corey–Chaykovsky reaction, followed byopening of the oxirane ring by the action of excess tert-butylamine. In the synthesis of 4-hydroxytulobuterol, thehydroxy group was protected by benzylation, and the protecting group was removedin the final stage by hydrogenation over carbon-supported palladium.