56317-21-6 Usage
Description
Veraphenol is a polyphenolic compound derived from the roots of Morus Alba, which is known for its tyrosinase inhibitory properties. It has demonstrated potential in various applications due to its ability to modulate biological processes and exhibit beneficial effects on health.
Uses
Used in Pharmaceutical Applications:
Veraphenol is used as a tyrosinase inhibitor for its ability to regulate the activity of tyrosinase, an enzyme involved in the production of melanin. This application is particularly relevant in the treatment of hyperpigmentation and related skin conditions.
Used in Antidiabetic Applications:
Veraphenol is used as a hypoglycemic agent for its ability to reduce glucose levels and lipid peroxidation while increasing insulin levels in rats with streptozotocin-induced diabetes mellitus. This suggests its potential use in managing and treating diabetes and related metabolic disorders.
Used in Antioxidant Applications:
Given its polyphenolic nature, Veraphenol is likely to be used as an antioxidant in various industries, including the pharmaceutical, cosmetic, and food industries. Its antioxidant properties can help protect cells from damage caused by reactive oxygen species and support overall health and well-being.
Used in Cosmetic Applications:
In the cosmetic industry, Veraphenol may be used as an active ingredient in skincare products due to its tyrosinase inhibitory and antioxidant properties. These characteristics can contribute to the development of products aimed at improving skin tone, reducing the appearance of hyperpigmentation, and providing protection against environmental stressors.
Used in Food Industry:
Veraphenol's antioxidant properties can also be harnessed in the food industry to improve the shelf life and quality of various products. It can be used as a natural preservative to protect against oxidation and spoilage, maintaining the freshness and nutritional value of the food items.
Synthesis Reference(s)
Tetrahedron Letters, 28, p. 2645, 1987 DOI: 10.1016/S0040-4039(00)96171-9
Check Digit Verification of cas no
The CAS Registry Mumber 56317-21-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,1 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56317-21:
(7*5)+(6*6)+(5*3)+(4*1)+(3*7)+(2*2)+(1*1)=116
116 % 10 = 6
So 56317-21-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H10O4/c15-10-2-1-8-5-13(18-14(8)7-10)9-3-11(16)6-12(17)4-9/h1-7,15-17H
56317-21-6Relevant articles and documents
Synthesis of moracin C and its derivatives with a 2-arylbenzofuran motif and evaluation of their PCSK9 inhibitory effects in HepG2 cells
BasavanaGowda, Melanayakanakatte Kuberappa,Chae, Hee-Sung,Choi, Won Jun,Masagalli, Jagadeesh Nagarajappa
, (2021/05/31)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key factor in several cardiovascular diseases, as it is responsible for the elevation of circulating low-density lipoprotein cholesterol (LDL-C) levels in blood plasma by direct interaction with t
Deconstructive Reorganization: De Novo Synthesis of Hydroxylated Benzofuran
Cao, Tongxiang,Jiang, Huanfeng,Zhang, Ling,Zhu, Shifa
, p. 4670 - 4677 (2020/02/20)
An unprecedented deconstructive reorganization strategy for the de novo synthesis of hydroxylated benzofurans from kojic acid- or maltol-derived alkynes is reported. In this reaction, both the benzene and furan rings were simultaneously constructed, whereas the pyrone moiety of the kojic acid or maltol was deconstructed and then reorganized into the benzene ring as a six-carbon component. Through this strategy, at least one free hydroxyl group was introduced into the benzene ring in a substitution-pattern tunable fashion without protection–deprotection and redox adjustment. With this method, a large number of hydroxylated benzofuran derivatives with different substitution-patterns have been prepared efficiently. This methodology has also been shown as the key step in a collective total synthesis of hydroxylated benzofuran-containing natural products (11 examples).
A protecting group-free divergent synthesis of natural benzofurans via one-pot synthesis of 2-bromo-6-hydroxybenzofurans
Sivaraman, Aneesh,Harmalkar, Dipesh S.,Kang, Jiyoon,Choi, Yongseok,Lee, Kyeong
, p. 2153 - 2161 (2019/02/27)
2-Bromo-6-hydroxybenzofurans are potentially versatile intermediates for the divergent synthesis of numerous benzofuran-based natural products and their analogues. Herein we report the first one-pot strategy for the efficient synthesis of 2-bromo-6-hydrox
