5597-27-3 Usage
Description
3-Methylene-2-norbornanone is a chemical compound with the molecular formula C8H10O. It is a bicyclic ketone with a methylene group attached to the norbornane ring system. 3-METHYLENE-2-NORBORNANONE is known for its unique structure and reactivity, making it a versatile building block in organic synthesis.
Uses
Used in Organic Synthesis:
3-Methylene-2-norbornanone is used as a reactant in the preparation of various organic compounds. Its reactivity and unique structure make it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
3-Methylene-2-norbornanone is used as a reactant to prepare 3-(2-(4-methoxyphenyl)-2-oxoethyl)bicyclo[2.2.1]heptan-2-one by reacting with 4-anisaldehyde in the presence of tetrabutylammonium decatungstate (TBADT) photocatalyst. 3-METHYLENE-2-NORBORNANONE may have potential applications in the development of pharmaceutical agents.
Used in Chemical Research:
3-Methylene-2-norbornanone is also used in the preparation of 2-aryl-3-methylene-endo-norbornanols by treating with corresponding aryl lithium reagents. This reaction provides insights into the reactivity of the norbornane ring system and contributes to the understanding of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 5597-27-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,9 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5597-27:
(6*5)+(5*5)+(4*9)+(3*7)+(2*2)+(1*7)=123
123 % 10 = 3
So 5597-27-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10O/c1-5-6-2-3-7(4-6)8(5)9/h6-7H,1-4H2/t6-,7+/m1/s1
5597-27-3Relevant articles and documents
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Erman,W.F.
, p. 765 - 771 (1967)
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Process for the preparation of bicyclic diketone salts
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Page/Page column 4, (2008/06/13)
The present invention relates to a process for the preparation of bicyclic 1,3-diketone salts of formula I wherein R1, R2, R3 and R4 are each independently of the others hydrogen or C1-C4alkyl; A and E are each independently of the other C1-C2alkylene, which may be substituted once or up to four times by a C1-C4alkyl group, and M+ is an alkali metal ion, alkaline earth metal ion or ammonium ion, by oxidation of a compound of formula II to a compound of formula III and subsequent conversion to a compound of formula I either in the presence of a base and a catalytic amount of a cyanide or in the presence of an alkali metal alcoholate or alkaline earth metal alcoholate, and to novel bicyclic enol lactone intermediates of formula III for use in that process.
Radical Reactions of Bicycloheptan-3-spiro-2'-oxiranes
Bowman, W. Russell,Brown, David S.,Burns, Catherine A.,Marples, Brian A.,Zaidi, Naveed A.
, p. 6883 - 6896 (2007/10/02)
Tributyltin hydride reduction of 2-bromo- and 2-keto-bicycloheptan-3-spiro-2'-oxiranes gives ring opening of the oxirane-ringes via intermediate 3-(spiro-2'-oxiranyl)bicycloheptan-2-yl radicals, whereas reduction of the analogous 2-(thiocarbonyl)imidazolides) unusually yields the 2-methoxy derivatives and does not proceed by the expected normal fragmentation to yield 3-(spiro-2'-oxiranyl)bicycloheptan-2-yl radicals and subsequent ring-opening of the oxirane rings.