558-22-5

Basic information

• Product Name: TRIFLUOROMETHANE-D
• Synonyms: TRIFLUOROMETHANE-D;Trifluoromethane-D (gas)
• CAS NO: 558-22-5
• Molecular Formula: CHF₃
• Molecular Weight: 71.02
• Mol File: 558-22-5.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Density: 1.149 g/cm³
• Vapor Pressure: 25200mmHg at 25°C
• Refractive Index: 1.179
• CAS DataBase Reference: TRIFLUOROMETHANE-D(CAS DataBase Reference)
• NIST Chemistry Reference: TRIFLUOROMETHANE-D(558-22-5)
• EPA Substance Registry System: TRIFLUOROMETHANE-D(558-22-5)

Safety Data

• Hazardous Substances Data: 558-22-5(Hazardous Substances Data)

Usage

Description

TRIFLUOROMETHANE-D is a stable, colorless, non-flammable gas that contains three isotopes of fluorine. It is known for its low toxicity, non-reactivity with other chemicals, and chemical stability, making it suitable for various industrial applications.

Uses

Used in Refrigeration Industry:
TRIFLUOROMETHANE-D is used as a refrigerant for its low toxicity and non-reactivity with other chemicals, either on its own or in combination with other refrigerants.
Used in Aerosol Products Industry:
TRIFLUOROMETHANE-D is used as a propellant in aerosol products due to its properties that make it suitable for such applications.
Used in Electronics Manufacturing:
TRIFLUOROMETHANE-D is used as a cleaning agent in electronics manufacturing, taking advantage of its chemical stability and low boiling point for effective cleaning processes.
However, it is important to note that TRIFLUOROMETHANE-D is a potent greenhouse gas with a high global warming potential. Consequently, there is an ongoing effort to find more environmentally friendly alternatives for its applications.

InChI:InChI=1/CHF3/c2-1(3)4/h1H/i1D

Upstream product

• 811-98-3 d⁽⁴⁾-methanol 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 1680206-12-5 Grushin’s reagent 
• 2206-26-0 [D₃]acetonitrile 
• 887144-94-7 Togni's reagent II 
• 3317-61-1 5,5-Dimethyl-1-pyrroline N-oxide 
• 1665-00-5 dichloromethane-d2 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 79552-31-1 2,2,6,6-tetramethylpiperidine-1-D 
• 325810-07-9 tris(triphenylphosphane)(trifluoromethyl)copper(I) 
• 865-49-6 chloroform-d1 
• 2264-21-3 trifluoromethyl radical 
• 13536-94-2 deuterium sulfide 
• 54128-17-5 trifluoromethanide 

Downstream Products

• 13760-79-7 thulium(III) fluoride 
• 13760-78-6 holmium(III) fluoride 
• 13765-26-9 gadolinium(III) fluoride 
• 13760-83-3 erbium(III) fluoride 
• 7758-88-5 cerium(III) fluoride 
• 13709-46-1 praseodymium(III) fluoride 
• 13709-42-7 neodymium(III) fluoride 
• 13709-38-1 lanthanum(III) fluoride 
• 13760-81-1 lutetium(III) fluoride 
• 75-46-7 trifluoromethan 

Relevant articles and documents

1,2-(Bis)trifluoromethylation of Alkynes: A One-Step Reaction to Install an Underutilized Functional Group

Modifying the electronic properties of olefins is the quintessential approach to tuning alkene reactivity. In this context, the exploration of trifluoromethyl groups as divergent electronic modifiers has not been considered. In this work, we describe a copper-mediated 1,2-(bis)trifluoromethylation of acetylenes to create E-hexafluorobutenes (E-HFBs) under blue light in a single step. The reaction proceeds with high yield and E/Z selectivity. Since the alkyne captures two trifluoromethyl groups from each molecule of bpyCu(CF3)3, mechanistic studies were conducted to illuminate the role of the reactants. Interestingly, E-HFBs exhibit remarkable stability to standard olefin functionalization reactions in spite of the pendant trifluoromethyl groups. This finding has significant implications for medicine, agroscience, and materials.

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Carbon-Carbon Bond-Forming Reductive Elimination from Isolated Nickel(III) Complexes

This manuscript describes the design, synthesis, characterization, and reactivity studies of organometallic NiIII complexes of general structure TpNiIII(R)(R1) (Tp = tris(pyrazolyl)borate). With appropriate selection of th

Nucleophile-catalyzed, facile, and highly selective C-H activation of fluoroform with Pd(II)

Exceedingly facile (23 C) and chemoselective H-CF3 activation with [(dppp)Pd(Ph)(OH)] in the presence of a Lewis base promoter such as n-Bu3P leads to Pd-CF3 bond formation in nearly quantitative yield. A combined experimental and computational study points to a new mechanism that involves H-bonding Pd-O(H)···H-CF 3 and nucleophilic attack of the promoter on the metal, followed by a push-pull-type collapse of the resultant five-coordinate Pd(II) intermediate via a polar transition state.