55497-79-5

Basic information

• Product Name: Myriceric acid B
• Synonyms: Myriceric acid B
• CAS NO: 55497-79-5
• Molecular Formula: C₃₉H₅₄O₇
• Molecular Weight: 634.84186
• Mol File: 55497-79-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Myriceric acid B(CAS DataBase Reference)
• NIST Chemistry Reference: Myriceric acid B(55497-79-5)
• EPA Substance Registry System: Myriceric acid B(55497-79-5)

Safety Data

• Hazardous Substances Data: 55497-79-5(Hazardous Substances Data)

Usage

General Description

Myriceric acid B is a compound derived from the bark of Myrica rubra, a small evergreen tree native to East Asia. It belongs to a class of chemicals known as triterpenoids, which are known for their potential biological and pharmacological activities. Studies have revealed that myriceric acid B possesses anti-inflammatory and anti-tumor properties, making it a promising candidate for the development of new drugs for various diseases. Its structure consists of a pentacyclic triterpenoid backbone with multiple hydroxyl groups, which are likely responsible for its medicinal properties. Research on myriceric acid B is ongoing, with the hope of uncovering its full potential for therapeutic use.

Downstream Products

• 155748-94-0 rhoipteleic acid B 
• 155661-13-5 rhoipteleic acid A 

Relevant articles and documents

Endothelin receptor antagonist triterpenoid, myriceric acid A, isolated from Myrica cerifera, and structure activity relationships of its derivatives

As the first non-peptide endothelin receptor antagonist from a higher plant, a new triterpenoid, myriceric acid A (50-235) (1) was isolated from the bayberry, Myrica cerifera. Myriceric acid A (1) inhibited not only an endothelin-1-induced increase in cytosolic free Ca2+ concentration (IC50 = 11 ± 2 nM) but [125I]endothelin-1 binding in rat aortic smooth muscle cells (K(i)=66 ±15 nM). Two new related triterpenoids, myriceric acid C (6), and myriceric acid D (8), were also isolated. Furthermore, the chemical modification of these natural products led to the synthesis of sulfated derivatives (13, 14, 15) which showed 1.5 to 20 times higher affinity for endothelin receptors. The structure activity relationships of myriceric acids and their derivatives are discussed.