554-72-3 Usage
Description
Tryparsamide, an organoarsenic compound, is recognized for its historical role as an antiprotozoal agent, specifically in the treatment of trypanosomiasis. It functions by disrupting the energy metabolism of the parasite, which results in the death of the pathogen. Classified as a highly toxic compound, tryparsamide is associated with severe side effects, such as renal and liver toxicity, and has been largely replaced by safer and more effective treatments.
Uses
Used in Medical Applications:
Tryparsamide is used as an antiprotozoal agent for the treatment of African sleeping sickness, which is caused by the parasite Trypanosoma brucei. Its application in this context is due to its ability to interfere with the energy metabolism of the parasite, leading to its death. However, due to its high toxicity and serious side effects, including renal and liver toxicity, tryparsamide is no longer recommended as a first-line treatment for trypanosomiasis. The decline in its use is also attributed to the availability of safer and more effective treatment options in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 554-72-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,5 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 554-72:
(5*5)+(4*5)+(3*4)+(2*7)+(1*2)=73
73 % 10 = 3
So 554-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H11AsN2O4.Na/c10-8(12)5-11-7-3-1-6(2-4-7)9(13,14)15;/h1-4,11H,5H2,(H2,10,12)(H2,13,14,15);/q;+1/p-1