55119-29-4

Basic information

• Product Name: (Dimethyl-2,6-dihydro-1,4-pyridyliden-4-yl)-2-indandion-1,3
• CAS NO: 55119-29-4
• Molecular Weight: 251.285
• Mol File: 55119-29-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Dimethyl-2,6-dihydro-1,4-pyridyliden-4-yl)-2-indandion-1,3(CAS DataBase Reference)
• NIST Chemistry Reference: (Dimethyl-2,6-dihydro-1,4-pyridyliden-4-yl)-2-indandion-1,3(55119-29-4)
• EPA Substance Registry System: (Dimethyl-2,6-dihydro-1,4-pyridyliden-4-yl)-2-indandion-1,3(55119-29-4)

Safety Data

• Hazardous Substances Data: 55119-29-4(Hazardous Substances Data)

Upstream product

• 108-75-8 2,4,6-trimethyl-pyridine 
• 80673-06-9 phtalate acide de (piperidinyl)-2 ethanol 
• 85-44-9 phthalic anhydride 

Downstream Products

• 76080-08-5 <(Dichloro-2,6 benzyl)-1 dimethyl-2,6 dihydro-1,4 pyridylidene-4 yl>-2 indanedione-1,3 
• 76080-07-4 (Dichloro-2,6 benzyl)-2 (dimethyl-2,6 pyridyl-4)-2 indanedione-1,3 

Relevant articles and documents

Synthesis and pharmacological evaluation of 2-(2 and 4- pyridinyl)indane-1,3-diones and structuraly related compounds exerting potential anti-inflammatory and antitumoral activities

Our on going work in the series of enamido-diketones issued from 2- azaarylindane-1,3-diones led us to synthesize and experiment N and C2- substituted derivatives of 2-(2 and 4-pyridinyl)indane-1,3-diones as well as of structurally related compounds resulting from the replacement of pyridine by quinoline and benzimidazole. Pharmacological evaluation of their anti- inflammatory activity (by inhibition of carrageenan foot edema) and their anticoagulant activity (by prothombin assay) led to the conclusion of the possibility of achieving a selective antiinflammatory effect. It has been previously established that anticoagulants are liable to exert a protective effect in the development of cancer metastasis. Nevertheless none of the six experimented 2-(pyridin-2-yl)indane-1,3-diones extended survival time of mice treated by P388 lymphocytic leukemia.