55056-80-9

Basic information

• Product Name: Protodioscin
• Synonyms: SHENGMATING;PROTODIOSCIN;PROTODIOSON;26-o-beta-d-glycopyranosyl-22-hydroxyfurost-5-ene-3beta,26-diol-3-o-beta-diglucorhamnoside;PROTODIOSCIN SNAP-N-SHOOT 0.1mg/mL(P);PROTODIOSCIN(P);β-D-Glucopyranoside, (3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-ylO-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-;[(22R,25R)-22-Hydroxy-26-(β-D-glucopyranosyloxy)furosta-5-ene-3β-yl]2-O,4-O-bis(α-L-rhamnopyranosyl)-β-D-glucopyranoside
• CAS NO: 55056-80-9
• Molecular Formula: C₅₁H₈₄O₂₂
• Molecular Weight: 1049.2
• Product Categories: Miscellaneous Natural Products;The group of Dioscin;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 55056-80-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 190～192℃
• Appearance: Brown Yellow Powder
• Density: 1.46 g/cm³
• Refractive Index: 1.631
• Storage Temp.: 2-8°C
• Solubility: Methanol (Slightly), Pyridine (Slightly)
• PKA: 12?+-.0.70(Predicted)
• CAS DataBase Reference: Protodioscin(CAS DataBase Reference)
• NIST Chemistry Reference: Protodioscin(55056-80-9)
• EPA Substance Registry System: Protodioscin(55056-80-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 55056-80-9(Hazardous Substances Data)

Usage

Description

Protodioscin is a steroidal saponin compound derived from various plant species, predominantly recognized as the active component of the herbal aphrodisiac plant Tribulus terrestris. It exhibits significant hormonal level increases in animal studies and possesses a melting point of 190-196°C.

Uses

Used in Pharmaceutical Industry:
Protodioscin is used as a pharmaceutical agent for its aphrodisiac properties and potential enhancement of hormonal levels. It is particularly valued for its ability to stimulate sexual function and improve overall reproductive health.
Used in Herbal Medicine:
In the field of herbal medicine, Protodioscin is utilized for its traditional use as an aphrodisiac and its potential to support hormonal balance. It is often incorporated into supplements and remedies aimed at promoting sexual health and well-being.
Used in Sports Nutrition:
Protodioscin is also used in the sports nutrition industry, where it is believed to support increased energy levels, endurance, and muscle strength. Its hormonal influence may contribute to improved athletic performance and recovery.
Used in Research and Development:
In the research and development sector, Protodioscin serves as a key compound for studying the effects of steroidal saponins on hormonal regulation and their potential applications in medicine and pharmacology. This research may lead to the development of new drugs and therapies for various health conditions.

InChI:InChI=1/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1

Upstream product

• 54522-52-0 26-O-β-D-glucopyranosyl-22-O-methylfurost-5-ene-3β,26-diol 3-O-β-chacotrioside 
• 54522-52-0 C₅₂H₈₆O₂₂ 

Downstream Products

• 19057-68-2 diosgenin 3-O-α-L-rhamnopyranosyl(1->4)-β-D-glucopyranoside 
• 60478-68-4 dioscin 
• 50-99-7 D-glucose 

Relevant articles and documents

Synthesis of furostanol glycosides: Discovery of a potent α-glucosidase inhibitor

A convenient approach to the synthesis of furostanol glycosides has been developed with the features of both highly efficient incorporation of a 26-O-β-d-glucopyranosyl unit and ready formation of hemiketal ring E. The total syntheses of seven furostanol saponins including funlioside B, lilioglycoside, protobioside I, protodioscin, pallidifloside I, coreajaponins A and parisaponin I are efficiently achieved using an easily available 16β-acetoxy-22-oxo-26-hydroxy-cholestanic derivative as a powerful building block. The α-glucosidase inhibitory activity of the synthesized saponins is also evaluated, which reveals that funlioside B is a highly potential lead for developing α-glucosidase inhibitors.

Studies on the Constituents of Palmae Plants. I. The Constituents of Trachycarpus fortunei (HOOK.) H. WENDL. (1)

The constituents of the leaves, stems and underground parts of Trachycarpus fortunei (HOOK.) H.Wendl. (Palmae) have been investigated.Glucoluteolin (3), luteolin 7-O-rutinoside (=scolymoside, 4) and methyl proto-Pb (6) from the leaves, dioscin (1), Pb (2), methyl protodioscin (5) and methyl proto-Pb (6) from the stems, and dioscin (1) and methyl proto-Pb (6) from the underground parts were isolated and identified.This is the first report of the isolation of steroidal saponins from Palmae plants and these results are interesting from the standpoint of chemotaxonomy. keywords - Trachycarpus fortunei; Palmae; steroidal saponin; furostanol oligoside; diosgenin; proto-diosgenin; flavone glycoside; luteolin; glucoluteolin; scolymoside