55-43-6

Basic information

• Product Name: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
• Synonyms: dibenzylchlorethylaminehydrochloride;n-(2-chloroethyl)-dibenzylaminhydrochloride;n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride;N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE;N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE;N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE;N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE;N-(2-CHLOROETHYL)DIBENZYLAMINE HCL
• CAS NO: 55-43-6
• Molecular Formula: C₁₆H₁₈ClN*ClH
• Molecular Weight: 296.23
• EINECS: 200-234-5
• Product Categories: Amine Salts;Nitrogen Compounds;Organic Building Blocks;Amine Salts;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 55-43-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 190-193 °C(lit.)
• Boiling Point: 449.72°C (rough estimate)
• Flash Point: 147.3°C
• Appearance: White to off-white/Crystalline Powder
• Density: 1.1507 (rough estimate)
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: almost transparency in Methanol
• Merck: 14,2138
• CAS DataBase Reference: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)
• EPA Substance Registry System: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: HQ6825000
• HazardClass: IRRITANT
• Hazardous Substances Data: 55-43-6(Hazardous Substances Data)

Usage

Description

N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE is a chemical compound with the molecular formula C16H21Cl2N. It is a derivative of dibenzylamine, featuring a chloroethyl group attached to the nitrogen atom, and is presented as a hydrochloride salt. N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE is known for its potential biological activities and is often studied for its effects on various receptors and pathways in the body.

Uses

Used in Pharmaceutical Industry:
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE is used as a 5-Hydroxytryptamine antagonist for its ability to preferentially block postsynaptic alpha receptors. This application is particularly relevant in the study and treatment of various conditions related to the serotonin system, such as mood disorders and other neurological conditions.
Used in Research Applications:
In research settings, N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE serves as a valuable tool for investigating the mechanisms of action and the role of specific receptors in physiological and pathological processes. Its use in research can contribute to the development of new therapeutic strategies and a better understanding of receptor biology.

Upstream product

• 100-39-0 benzyl bromide 
• 101-06-4 N,N-dibenzyl-2-aminoethanol 

Downstream Products

• 103042-67-7 1-(2-dibenzylamino-ethyl)-4-phenyl-piperazine 
• 53197-73-2 2,7-Bis-(2-dibenzylamino-ethoxy)-fluoren-9-one 
• 152193-84-5 methyl N-(2-dibenzylaminoethyl)indole-2-carboxylate 
• 884850-52-6 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N,N-dibenzylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 797052-52-9 8-(2-dibenzylaminoethoxy)-1-ethyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 797793-70-5 7-(2-dibenzylamino-ethoxy)-1-ethyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 149423-72-3 4-dibenzylamino-2-phenyl-butyronitrile 
• 180532-46-1 ethyl 1-[2-(dibenzylamino)-ethyl]-4-piperidinecarboxylate 
• 57151-12-9 1-(N,N-dibenzylamino)-2-(4-benzyloxyphenoxy)-ethane 
• 51-50-3 N,N-dibenzyl-2-chloroethanamine 
• 1349193-22-1 8-dibenzylamino-3,6-dioxaoctan-1-ol 

Relevant articles and documents

Preparation method of amino polyethylene glycol propionic acid

The invention relates to the field of organic synthesis, in particular to a preparation method of amino polyethylene glycol propionic acid. The preparation method comprises the steps that catalytic hydrogenation is carried out on dibenzyl amino polyethylene glycol tert-butyl propionate shown in formula I-2 to obtain amino polyethylene glycol tert-butyl propionate shown in formula I-3; (2) the amino polyethylene glycol tert-butyl propionate shown in formula I-3 is hydrolyzed under the acidic condition to obtain amino polyethylene glycol propionic acid shown in formula I. The preparation methodof the amino polyethylene glycol propionic acid has the advantages that the defects in the prior art that the yield is low, the dangerousness is high, and the enlargement of production is difficult are overcome, the reaction conditions are mild, the operation is simple, an intermediate does not to be purified, the next reaction can be directly carried out, the whole yield reaches up to 87-92%, thepurity of end products reaches up to 97-99.5%, and a safe and efficient synthetic route is provided for the preparation of amino polyethylene glycol propionic acid.