5469-48-7 Usage
Description
(2E)-2-(2-phenylethyl)but-2-enedioic acid, commonly known as fumaric acid, is an organic acid with the molecular formula C10H10O4. It is naturally found in various fruits and vegetables and is utilized as a food additive and in the production of certain polymers. Fumaric acid possesses a sour taste, making it a popular flavor enhancer in the food and beverage industry. Beyond its culinary uses, it also serves in industrial applications such as the production of resins, plastics, and pharmaceuticals. Moreover, fumaric acid has garnered interest for its potential therapeutic effects, particularly in the treatment of conditions like psoriasis and other skin disorders.
Uses
Used in Food and Beverage Industry:
Fumaric acid is used as a flavor enhancer for its sour taste, adding a distinctive tangy flavor to various foods and beverages.
Used in Pharmaceutical Industry:
Fumaric acid serves as a key component in the production of pharmaceuticals, contributing to the development of drugs for treating specific health conditions.
Used in Polymer Production:
It is utilized in the manufacturing process of certain polymers, playing a crucial role in the formation and properties of these materials.
Used in Skin Care and Treatment:
Fumaric acid has been studied for its potential therapeutic effects, particularly as a treatment for psoriasis and other skin conditions, offering a promising avenue for medical applications.
Used in Industrial Applications:
It is employed as a component in the production of resins and plastics, highlighting its versatility and importance in various industrial sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 5469-48-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5469-48:
(6*5)+(5*4)+(4*6)+(3*9)+(2*4)+(1*8)=117
117 % 10 = 7
So 5469-48-7 is a valid CAS Registry Number.
5469-48-7Relevant articles and documents
Asymmetric synthesis of 2-substituted butane-1,4-diols by hydrogenation of homochiral fumaramide derivatives
Jawaid, Samaila,Farrugia, Louis J.,Robins, David J.
, p. 3979 - 3988 (2007/10/03)
Diastereoselective hydrogenation of homochiral fumaramides 1 derived from (2R)-Oppolzer's sultam was observed by analysis of the 1H NMR spectra of the succinamide mixtures with de's of 77-88%. Reduction of these succinamides using LiAlH4 gave the corresponding (2S)-butane-1,4- diols and established that addition of hydrogen takes place selectively on the re-face of fumaramides 1. The stereoselectivity was confirmed by estimating the ee's from the 19F NMR spectra of the Mosher's diesters of the diols. This methodology was applied to the synthesis of selected pyrrolidine natural products in homochiral form.
