54673-12-0

Basic information

• Product Name: Benzene, [2-(methoxymethoxy)ethyl]-
• CAS NO: 54673-12-0
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 54673-12-0.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Benzene, [2-(methoxymethoxy)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [2-(methoxymethoxy)ethyl]-(54673-12-0)
• EPA Substance Registry System: Benzene, [2-(methoxymethoxy)ethyl]-(54673-12-0)

Safety Data

• Hazardous Substances Data: 54673-12-0(Hazardous Substances Data)

Upstream product

• 3587-61-9 1-chloromethyl 2-phenylethyl ether 
• 124-41-4 sodium methylate 
• 109-87-5 Dimethoxymethane 
• 82529-79-1 4-methoxybenzyl phenethyl ether 
• 60-12-8 2-phenylethanol 
• 107-30-2 chloromethyl methyl ether 
• 105104-40-3 Okahara's reagent 
• 103-82-2 phenylacetic acid 
• 13057-17-5 bromethyl methyl ether 

Downstream Products

• 493-05-0 isochromane 
• 60-12-8 2-phenylethanol 
• 103-45-7 acetic acid phenethyl ester 
• 17376-04-4 2-phenethyl iodide 
• 103-63-9 1-phenyl-2-bromoethane 
• 645-59-0 dihydrocinnamonitrile 
• 1355017-07-0 C₁₇H₁₄O 
• 1338236-26-2 C₁₇H₁₄O 
• 1338236-27-3 C₁₈H₁₆O 
• 1338236-28-4 C₁₈H₁₆O 
• 1338236-29-5 C₁₈H₁₆O 
• 1338236-30-8 C₁₉H₁₈O 
• 1338236-31-9 C₁₈H₁₃F₃O 
• 1338236-32-0 C₂₀H₁₈O₃ 

Relevant articles and documents

Ytterbium-Catalyzed Intramolecular [3 + 2] Cycloaddition based on Furan Dearomatization to Construct Fused Triazoles

The 1,2,3-triazole-containing polycyclic architecture widely exists in a broad spectrum of synthetic bioactive molecules, and the development of expeditious methods to synthesize these skeletons remains a challenging task. In this work, the catalytic cyclization of biomass-derived 2-furylcarbinols with an azide to form fused triazoles is described. This approach takes advantage of a single catalyst Yb(OTf)3 and operates via a furfuryl-cation-induced intramolecular [3 + 2] cycloaddition/furan ring-opening cascade.

Enantioselective synthesis of tetrahydroisoquinoline derivatives via chiral-at-metal rhodium complex catalyzed [3+2] cycloaddition

An asymmetric [3+2] cycloaddition of C,N-cyclic azomethine imines with α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium complex has been developed. The corresponding C-1-substituted tetrahydroisoquinoline derivatives were obtained in high yields (>90%) with excellent stereoselectivities (up to 99% ee and >20?:?1 dr). The reaction can be conducted on a gram-scale using a low catalyst loading (0.5 mol%) with high yield and selectivity.

Scaffold Diversity through a Branching Double-Annulation Cascade Strategy: Iminium-Induced One-Pot Synthesis of Diverse Fused Tetrahydroisoquinoline Scaffolds

A branching double-annulation cascade (BDAC) strategy for diverse and complex fused THIQ scaffolds via a highly reactive iminium-induced one-pot double-cyclization sequence involving Pictect-Spengler-type cyclization has been developed for the first time. The salient features of this protocol are that it allows direct and rapid access to unprecedented diverse fused THIQ skeletons, is metal/catalyst free, has a cleaner reaction profile, provides good to excellent yields, and is a convenient approach. This catalyst-free domino process facilitates the double annulation with a variety of scaffold building agents via two C-N and one C-X (X = C, N, O) bond formation in a single step under uniform reaction conditions. Furthermore, we reveal an unusual dual BDAC sequence leading to N-N-linked isoquinoline dimer.