5293-84-5 Usage
Description
(Chloromethyl)triphenylphosphonium Chloride is a versatile and potent Wittig reagent, characterized by its white to almost white fine crystalline powder appearance. It is widely utilized in various chemical reactions and processes due to its unique chemical properties and reactivity.
Uses
Used in Organic Chemistry:
(Chloromethyl)triphenylphosphonium Chloride is used as a Wittig reagent for the synthesis of alkenes, which are essential components in the production of various pharmaceuticals, agrochemicals, and other organic compounds. Its application in this field is due to its ability to facilitate the formation of carbon-carbon double bonds, a crucial step in the synthesis of many complex organic molecules.
Used in Corrosion Inhibition:
In the metallurgical industry, (Chloromethyl)triphenylphosphonium Chloride is used as a corrosion inhibitor for iron. Its effectiveness in preventing the oxidation and degradation of iron surfaces makes it a valuable additive in the protection of metal structures and components.
Used in Electrophilic Reactions:
(Chloromethyl)triphenylphosphonium Chloride acts as a potential electrophile in various chemical reactions, enabling the formation of new carbon-heteroatom bonds. This property is particularly useful in the synthesis of complex organic molecules and the modification of existing structures.
Used in Synthesis of Linear Alkynes:
As a reactant in elimination reactions, (Chloromethyl)triphenylphosphonium Chloride is employed in the synthesis of linear alkynes. These compounds are important intermediates in the production of various chemicals, materials, and pharmaceuticals.
Used in Intramolecular Nucleophilic Vinylic Substitution:
In the field of organic synthesis, (Chloromethyl)triphenylphosphonium Chloride is utilized in intramolecular nucleophilic vinylic substitution reactions. This process allows for the formation of cyclic structures with a vinyl group, which are essential in the development of various pharmaceuticals and agrochemicals.
Used in Homologation of Aldehydes:
(Chloromethyl)triphenylphosphonium Chloride is used in the homologation of aldehydes, a process that involves the conversion of an aldehyde to a higher homolog. This reaction is crucial in the synthesis of various organic compounds, including those with potential applications in the pharmaceutical and chemical industries.
Used in Endo-selective Alkynol Cycloisomerization:
In the field of organic chemistry, (Chloromethyl)triphenylphosphonium Chloride is employed in endo-selective alkynol cycloisomerization reactions. This process allows for the selective formation of cyclic structures from alkynols, which are important intermediates in the synthesis of complex organic molecules and natural products.
Check Digit Verification of cas no
The CAS Registry Mumber 5293-84-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,9 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5293-84:
(6*5)+(5*2)+(4*9)+(3*3)+(2*8)+(1*4)=105
105 % 10 = 5
So 5293-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H17ClP/c20-16-21(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15H,16H2/q+1
5293-84-5Relevant articles and documents
Synthesis of Decorated Carbon Structures with Encapsulated Components by Low-Voltage Electric Discharge Treatment
Bodrikov, I. V.,Pryakhina, V. I.,Titov, D. Yu.,Titov, E. Yu.,Vorotyntsev, A. V.
, p. 60 - 69 (2022/03/17)
Abstract: Polycondensation of complexes of chloromethanes with triphenylphosphine by the action of low-voltage electric discharges in the liquid phase gives nanosized solid products. The elemental composition involving the generation of element distribution maps (scanning electron microscopy–energy dispersive X?ray spectroscopy mapping) and the component composition (by direct evolved gas analysis–mass spectrometry) of the solid products have been studied. The elemental and component compositions of the result-ing structures vary widely depending on the chlorine content in the substrate and on the amount of triphenylphosphine taken. Thermal desorption analysis revealed abnormal behavior of HCl and benzene present in the solid products. In thermal desorption spectra, these components appear at an uncharacteristically high temperature. The observed anomaly in the behavior of HCl is due to HCl binding into a complex of the solid anion HCI-2 with triphenyl(chloromethyl)phosphonium chloride, which requires a relatively high temperature (up to 800 K) to decompose. The abnormal behavior of benzene is associated with its encapsulated state in nanostructures. The appearance of benzene begins at 650 K and continues up to temperatures above 1300?K.
The synthesis of benzylphosphine oxidesvia vicarious nucleophilic substitution and alkenes via VNS-Horner-Wittig reactions
Lawrence, Nicholas J.,Liddle, John,Jackson, David
, p. 2260 - 2267 (2007/10/03)
A range of substituted nitrobenzenes react with the anion of (chloromethyl)diphenylphosphinoyl oxide to give the substituted nitrobenzyldiphenylphosphine oxide by vicarious nucleophilic substitution. The novel stereoselective synthesis of E-stilbenes via a one-pot vicarious nucleophilic substitution-Horner-Wittig reaction is described.
