52794-97-5 Usage
Description
Carubicin, also known as Karminomycin Hydrochloride, is a potent antibiotic and anthracycline antineoplastic antibiotic derived from hydrolyzable tannins found in gall nuts and various plant sources. It possesses strong anticancer properties and is highly active against human tumor cells and their multidrug resistant variants. Its quinone-containing structure enables interactions with biopolymers and macromolecules, making it a promising pharmaceutical candidate for various applications.
Uses
Used in Antineoplastic Applications:
Carubicin is used as an antineoplastic agent for its potent anticancer properties. It is particularly effective against solid malignancies such as liver, breast, lung, pancreatic, colorectal, and ovarian cancers. It modulates several oncological signaling pathways, exerting inhibitory effects on tumor growth and progression.
Used in Pharmaceutical Industry:
Carubicin is used as a highly active quinone-containing anticancer drug in the pharmaceutical industry. Its unique structure and potent activity make it a valuable component in the development of new cancer treatments and therapies.
Used in Drug Development:
Carubicin is used in drug development for its potential to enhance chemo-sensitivity and efficacy in resistant cases when combined with conventional chemotherapeutic drugs. Its synergistic anticancer effects make it a promising candidate for the development of novel drug delivery systems and cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 52794-97-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,7,9 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52794-97:
(7*5)+(6*2)+(5*7)+(4*9)+(3*4)+(2*9)+(1*7)=155
155 % 10 = 5
So 52794-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C26H27NO10/c1-9-21(30)13(27)6-16(36-9)37-15-8-26(35,10(2)28)7-12-18(15)25(34)20-19(23(12)32)22(31)11-4-3-5-14(29)17(11)24(20)33/h3-5,9,13,15-16,21,29-30,32,34-35H,6-8,27H2,1-2H3/t9?,13?,15?,16?,21?,26-/m0/s1
52794-97-5Relevant articles and documents
Carminomycin derivatives, their preparation and use
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, (2008/06/13)
N-acyl derivatives of the known antitumor antibiotic carminomycin, particularly N-trifluoroacetyl carminomycin, have a much lower toxicity than carminomycin.
