52717-09-6

Basic information

• Product Name: 1-phenyl-2-perfluorohexyl acetylene
• Synonyms: 1-phenyl-2-perfluorohexyl acetylene
• CAS NO: 52717-09-6
• Molecular Weight: 420.173
• Mol File: 52717-09-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-phenyl-2-perfluorohexyl acetylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-perfluorohexyl acetylene(52717-09-6)
• EPA Substance Registry System: 1-phenyl-2-perfluorohexyl acetylene(52717-09-6)

Safety Data

• Hazardous Substances Data: 52717-09-6(Hazardous Substances Data)

Upstream product

• 344343-03-9 phenyl(perfluorohexyl)iodonium triflate 
• 4440-01-1 lithium phenylacetylide 
• 51300-88-0 (perfluoro n-octyl) magnesiumbromide 
• 100-58-3 phenylmagnesium bromide 
• 355-43-1 n-perfluorohexyl iodide 
• 536-74-3 phenylacetylene 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 1199-95-7 1-(trimethylstannyl)-2-phenylethyne 
• 103-64-0 bromostyrene 
• 932-88-7 1-iodo-2-phenylethyne 
• 507-63-1 1-iodoheptadecafluorooctane 

Downstream Products

• 55009-98-8 1-Phenyl-2-perfluorhexyl-3.3.4.4-tetrafluorcyclobut-1-en 
• 54864-77-6 3-(perfluoropentyl)-5-phenyl-1H-pyrazole 
• 55009-96-6 1-Phenyl-2-perfluorhexylcyclohexa-1.4-dien 

Relevant articles and documents

Silver-Mediated Perfluoroalkylation of Terminal Alkynes with Perfluoroalkyl Iodides

The incorporation of a perfluoroalkyl group (RF) into drug candidates has become an increasingly important strategy in drug molecule design. In this study, the silver-mediated perfluoroalkylation reaction based on the addition-elimination process of terminal alkynes which was initiated by a perfluoroalkyl radical to form a C(sp)-RF bond has been developed. The reaction proceeds under mild conditions using readily available, low-cost perfluoroalkyl iodides as the sources of the RF group. This method allows access to a variety of perfluoroalkylated alkynes.

Visible light photocatalytic cross-coupling and addition reactions of arylalkynes with perfluoroalkyl iodides

Visible light photocatalytic cross-coupling and addition reactions of arylalkynes with perfluoroalkyl iodides have been developed. Through slight modifications of the reaction conditions, reactions that are selective for the preparation of the C-C couplin

Perfluoroalkylations of Carbanions with (Perfluoroalkyl)-phenyliodonium Triflates (FITS Reagents)

FITS reagents reacted with primary alkylmagnesium halides in THF at -78 deg C to give the corresponding perfluoroalkyl(Rf)-alkanes in moderate to good yields.But an alkyl-lithium or -copper gave a poor yield of the Rf-product.The rea