52222-74-9 Usage
Description
KaeMpferol-4'-O-β-D-glucopyranoside, also known as a kaempferol O-glucoside, is a naturally occurring compound found in various plants. It is characterized by the attachment of kaempferol to a beta-D-glucopyranosyl moiety at position 7 through a glycosidic linkage. KaeMpferol-4'-O-β-D-glucopyranoside has gained attention for its potential health benefits and applications in various industries.
Uses
Used in Pharmaceutical Industry:
KaeMpferol-4'-O-β-D-glucopyranoside is used as a bioactive compound for its potential therapeutic properties. It has been studied for its antioxidant, anti-inflammatory, and anti-cancer activities, making it a promising candidate for the development of new drugs and treatments.
Used in Cosmetic Industry:
In the cosmetic industry, KaeMpferol-4'-O-β-D-glucopyranoside is used as an ingredient for its skin-friendly properties. It is valued for its antioxidant and anti-inflammatory effects, which can help protect the skin from environmental stressors and promote a healthy complexion.
Used in Functional Foods:
KaeMpferol-4'-O-β-D-glucopyranoside is also used in the development of functional foods and dietary supplements. Its antioxidant and anti-inflammatory properties can contribute to overall health and well-being when consumed as part of a balanced diet.
Used in Drug Delivery Systems:
Similar to gallotannin, KaeMpferol-4'-O-β-D-glucopyranoside can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes. Researchers are exploring the use of various carriers, such as organic and metallic nanoparticles, to improve the delivery and efficacy of this compound in treating specific health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 52222-74-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,2 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 52222-74:
(7*5)+(6*2)+(5*2)+(4*2)+(3*2)+(2*7)+(1*4)=89
89 % 10 = 9
So 52222-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H20O11/c22-7-13-15(25)17(27)19(29)21(32-13)30-10-3-1-8(2-4-10)20-18(28)16(26)14-11(24)5-9(23)6-12(14)31-20/h1-6,13,15,17,19,21-25,27-29H,7H2/t13-,15-,17+,19-,21-/m1/s1
52222-74-9Relevant articles and documents
Functional Characterization and Protein Engineering of a Triterpene 3-/6-/2′-O-Glycosyltransferase Reveal a Conserved Residue Critical for the Regiospecificity
Bao, Yang-Oujie,Gao, Bai-Han,Li, Fu-Dong,Qiao, Xue,Shi, Xiao-Meng,Su, Hui-Fei,Wang, Hai-Dong,Ye, Min,Yi, Yang,Zhang, Meng
supporting information, (2022/01/06)
Engineering the function of triterpene glucosyltransferases (GTs) is challenging due to the large size of the sugar acceptors. In this work, we identified a multifunctional glycosyltransferase AmGT8 catalyzing triterpene 3-/6-/2′-O-glycosylation from the medicinal plant Astragalus membranaceus. To engineer its regiospecificity, a small mutant library was built based on semi-rational design. Variants A394F, A394D, and T131V were found to catalyze specific 6-O, 3-O, and 2′-O glycosylation, respectively. The origin of regioselectivity of AmGT8 and its A394F variant was studied by molecular dynamics and hydrogen deuterium exchange mass spectrometry. Residue 394 is highly conserved as A/G and is critical for the regiospecificity of the C- and O-GTs TcCGT1 and GuGT10/14. Finally, astragalosides III and IV were synthesized by mutants A394F, T131V and P192E. This work reports biocatalysts for saponin synthesis and gives new insights into protein engineering of regioselectivity in plant GTs.
Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol
Wang, Jingqiu,Fang, Xianying,Ge, Lin,Cao, Fuliang,Zhao, Linguo,Wang, Zhenzhong,Xiao, Wei
, (2018/05/28)
Kaempferol (kae) and its glycosides are widely distributed in nature and show multiple bio-activities, yet few reports have compared them. In this paper, we report the antitumor, antioxidant and anti-inflammatory activity differences of kae, kae-7-O-gluco
