5209-18-7Relevant articles and documents
Boron-catalyzed dehydrative allylation of 1,3-diketones and β-ketone esters with 1,3-diarylallyl alcohols in water
Zhang, Guo-Min,Zhang, Hua,Wang, Bei,Wang, Ji-Yu
, p. 17025 - 17031 (2021/05/25)
A metal-free catalytic allylation with atom economy and green environment friendly was developed. Allylic alcohols could be directly dehydrated in water by B(C6F5)3, without using any base additives. The reaction can afford the corresponding monoallylated product in moderate to high yield and has been performed on a gram-scale, and a quaternary carbon center can be constructed for the active methine compounds of 1,3-diketones or β-ketone esters in this process. The product can be further converted, such as the synthesis of tetra-substituted pyrazole compounds, or 1,4-dienes and functionalized dihydropyrans.
NHC-Iridium-Catalyzed Deoxygenative Coupling of Primary Alcohols Producing Alkanes Directly: Synergistic Hydrogenation with Sodium Formate Generated in Situ
Lu, Zeye,Zheng, Qingshu,Yang, Siqi,Qian, Chun,Shen, Yajing,Tu, Tao
, p. 10796 - 10801 (2021/09/08)
The direct conversion of alcohols into long-chain alkanes is an attractive but extremely challenging approach for biomass upgrading. Here, we describe the highly selective deoxygenative coupling of aryl ethanols with primary alcohols to produce alkanes, using a bis-N-heterocyclic carbene iridium (bis-NHC-Ir) complex as the catalyst. Up to quantitative yields and selectivity with a broad substrate scope are attained in both homo- and cross-coupling reactions. Mechanistic studies reveal that the further synergistic hydrogenation of the alkene intermediates by the formate generated in situ in the presence of bis-NHC-Ir is crucial for alkane production.
Construction of 5H-Dibenzo[c,e]azepine Framework from Dibenzothiophene Dioxides and N-Benzylimines through SNAr Reactions
Furukawa, Tomoki,Kaga, Atsushi,Saito, Hayate,Yanagi, Tomoyuki,Yorimitsu, Hideki
, (2021/11/17)
Treatment of a mixture of dibenzothiophene dioxides and benzaldehyde N-benzylimines with potassium hexamethyldisilazide induces sequential intermolecular and intramolecular SNAr reactions to eventually form the corresponding 5H-dibenzo[c,e]azep