51765-10-7Relevant articles and documents
The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu5]-enkephalin from coumarin prodrug moieties
Zych, Lindsay A.,Yang, Wenqian,Liao, Yuan,Griffin, Kellee R.,Wang, Binghe
, p. 109 - 123 (2007/10/03)
A coumarin-based prodrug system has been developed in our laboratory for the preparation of esterase-sensitive prodrugs of amines, peptides, and peptidomimetics. The drug release rates from this prodrug system were found to be dependent on the structural