51052-74-5 Usage
Description
3-Hydroxy-1,1-dimethyl pyrrolidinium bromide is a metabolite that is found in the kidney and liver as a result of the oral administration of glycopyrrolate. It is a derivative of pyrrolidine, a heterocyclic compound with a nitrogen atom in the ring, and has a hydroxyl group attached to the third carbon and two methyl groups on the first carbon. The bromide ion is present as a counterion, giving the compound its ionic nature.
Uses
Used in Pharmaceutical Industry:
3-Hydroxy-1,1-dimethyl pyrrolidinium bromide is used as a metabolite in the pharmaceutical industry for its role in the metabolism of glycopyrrolate. Glycopyrrolate is a medication that is used to treat various conditions, such as excessive sweating, saliva production, and bronchial secretions. The presence of this metabolite in the kidney and liver indicates its involvement in the body's processing and elimination of glycopyrrolate, which can be important for understanding the drug's pharmacokinetics and potential side effects.
Used in Research and Development:
3-Hydroxy-1,1-dimethyl pyrrolidinium bromide can also be used as a research tool in the development of new drugs and therapies. Its unique structure and properties may provide insights into the design of novel compounds with similar or improved pharmacological effects. Additionally, studying its metabolism and interactions with biological systems can contribute to a better understanding of drug metabolism and the development of personalized medicine approaches.
Check Digit Verification of cas no
The CAS Registry Mumber 51052-74-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,0,5 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51052-74:
(7*5)+(6*1)+(5*0)+(4*5)+(3*2)+(2*7)+(1*4)=85
85 % 10 = 5
So 51052-74-5 is a valid CAS Registry Number.
51052-74-5Relevant articles and documents
GLYCOPYRRONIUM FATTY ACID SALTS AND METHODS OF MAKING SAME
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Paragraph 59, (2017/01/02)
Novel glycopyrronium fatty acid salts have been developed. Bi-phasic reaction conditions enable the desired counterion exchange reactions between glycopyrronium bromide and fatty acid salts of alkali metals and alkaline earth metals in methods to form glycopyrronium fatty acid salts. In preferred embodiments, an excess of the free fatty acid in the reaction mixture stabilizes the glycopyrronium fatty acid salt and reduces the formation of the impurity, Acid A. In some preferred embodiments, between 0.2 and 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture. In another embodiment, approximately 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture.
