50932-20-2 Usage
Description
Verproside, a natural product derived from the bark of the Quillaja saponaria tree, is a complex mixture of triterpenoid saponins. It possesses unique properties, including anti-inflammatory and immunomodulatory effects, making it a promising candidate for various therapeutic applications.
Uses
Used in Pharmaceutical Industry:
Verproside is used as an anti-inflammatory agent for its ability to inhibit TNF-α-induced MUC5AC expression, which helps in preventing oversecretion of mucus in asthma and chronic obstructive pulmonary disease (COPD) patients. This property makes it a potential therapeutic agent for the treatment of respiratory disorders characterized by excessive mucus production.
Additionally, Verproside's immunomodulatory effects can be utilized in the development of novel drug delivery systems to enhance the efficacy and safety of various pharmaceutical formulations. Its potential to modulate immune responses may also contribute to the development of new treatments for autoimmune and inflammatory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 50932-20-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,9,3 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 50932-20:
(7*5)+(6*0)+(5*9)+(4*3)+(3*2)+(2*2)+(1*0)=102
102 % 10 = 2
So 50932-20-2 is a valid CAS Registry Number.
50932-20-2Relevant articles and documents
Chlorinated iridoid glucosides from Veronica longifolia and their antioxidant activity
Jensen, Soren R.,Gotfredsen, Charlotte H.,Harput, U. Sebnem,Saracoglu, Iclal
experimental part, p. 1593 - 1596 (2010/12/24)
From Veronica longifolia were isolated three chlorinated iridoid glucosides, namely, asystasioside E (6) and its 6-O-esters 6a and 6b, named longifoliosides A and B, respectively. The structures of 6a and 6b were proved by analysis of their spectroscopic data and by conversion to the catalpol ester verproside (5a) or to catalpol (5), respectively. The configuration of the previously known vanilloyl analogue, urphoside B, was shown to be the 6β-epimer (6c) of the structure originally reported. Longifoliosides A (6a) and B (6b) were found to exhibit radical-scavenging activity against nitric oxide, superoxide, and 2,2-diphenyl-1-picrylhydrazyl radicals.
