50789-30-5Relevant articles and documents
Intramolecular cationic cyclizations initiated by electrocyclic cleavage of cyclopropanes. Synthesis of trienic cyclopentane derivatives
Gassman, Paul G.,Tan, Lushi,Hoye, Thomas R.
, p. 439 - 442 (1996)
The electrocyclic opening of dibromocyclopropane derivatives containing a tethered diene unit provides a good route to trienic cyclopentane derivatives. In one instance a bicyclic product arising from a formal 4 + 2 cycloaddition process was observed.
Asymmetric Synthesis of Secondary Alcohols and 1,2-Disubstituted Epoxides via Organocatalytic Sulfenylation
Rota, Filippo,Benhamou, Laure,Sheppard, Tom D.
supporting information, p. 33 - 36 (2015/12/26)
Enantioenriched secondary alcohols can be prepared via a short reaction sequence involving asymmetric organocatalytic sulfenylation of an aldehyde, organometallic addition, and desulfurization. This process provides access to enantioenriched alcohols with sterically similar groups attached to the alcohol carbon atom. The intermediate β-hydroxysulfides can also serve as precursors to enantioenriched 1,2-disubstituted epoxides via alkylation of the sulfur and subsequent base-mediated ring closure.
PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND
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Page/Page column 27, (2011/10/04)
Disclosed is a process of enantioselectively forming an aminoxy compound of Formula (3) In formula (3) R1 is one of an aliphatic group and an alicyclic group. R2 is one of hydrogen, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group and an arylalicyclic group. R3 is one of hydrogen, halogen, hydroxyl, and an aliphatic group with a main chain having 1 to about 10 carbon atoms. The respective aliphatic, alicyclic, aromatic, arylaliphatic or arylalicyclic groups of R1, R2, and R3 comprise 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si. The process includes contacting a carbonyl compound of Formula (1) and a nitroso compound of Formula (2) in the presence of a chiral catalyst. The chiral catalyst is a compound of Formula (IX)