502927-16-4

Basic information

• Product Name: (S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-propan-1-one
• CAS NO: 502927-16-4
• Molecular Weight: 637.956
• Mol File: 502927-16-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-propan-1-one(502927-16-4)
• EPA Substance Registry System: (S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-propan-1-one(502927-16-4)

Safety Data

• Hazardous Substances Data: 502927-16-4(Hazardous Substances Data)

Upstream product

• 175084-42-1 (4Z,6S)-<(tert-butyldiphenylsilyl)oxy>-4-heptenal 
• 125664-95-1 N-propionyl-(2R)-bornane-(10,2)-sultam 
• 502927-14-2 (Z)-(2S,3S,8S)-8-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-hydroxy-2-methyl-non-6-en-1-one 

Downstream Products

• 502927-17-5 (+)-methyl 8-epi-8-O-(tert-butyldiphenylsilyl)nonactate 
• 173396-36-6 methyl 8-benzoyl-(2S,3S,6R,8R)-nonactate 

Relevant articles and documents

A nucleophilic addition ring closure [NARC]-based synthesis of (+) -nonactic acid

Nonactic acid 1 has been synthesized in 12 steps from readily available (S)-(-)-ethyl lactate in 20% overall yield. The key ("NARC") sequence in this method involved anti-aldol addition of acylsultam 3 with aldehyde 4 followed by intramolecular oxymercura