49647-20-3Relevant articles and documents
Design, synthesis, and antitumor activity of novel sorafenib derivatives
Chen, Dan-Ping,Fan, Si-Li,Hou, Mi,Li, Xiao-Qin,Li, Zhu-Rui,Ouyang, Gui-Ping,Shao, Li-Hui,Wang, Zhen-Chao,Zou, Ya-Yu
, (2022/01/26)
New series of 18 compounds were synthesized using sorafenib derivatives as parent structure and p-aminoacetophenone as raw materials. The structures of the newly synthesized compounds were confirmed on the basis of 1H, 13C NMR and HR
Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin
Sun, Haiyang,Li, Hui,Wang, Jiayi,Song, Gonghua
, p. 977 - 980 (2017/11/16)
Nematodes are serious constraints of crop production worldwide. However, the traditional nematicides suffer from the side-effects, including environmental and human toxicity. Herein, more than 70 novel piperazinedione derivatives based on the natural product Barettin were synthesized and evaluated against the root-knot nematode Meloidogyne incognita (M. incognita). While most of synthesized compounds exhibited certain nematicidal activity at high concentration, the best one showed a nematicidal activity of 75% at 2.4 μmol/L.
Palladium-catalyzed synthesis of N-aryl carbamates
Vinogradova, Ekaterina V.,Park, Nathaniel H.,Fors, Brett P.,Buchwald, Stephen L.
supporting information, p. 1394 - 1397 (2013/04/24)
An efficient synthesis of aryl carbamates was achieved by introducing alcohols into the reaction of palladium-catalyzed cross-coupling of ArX (X = Cl, OTf) with sodium cyanate. The use of aryl triflates as electrophilic components in this transformation a
