49600-56-8

Basic information

• Product Name: 2-MERCAPTO-5,7-DIMETHYL-PYRIDO[2,3-D]PYRIMIDIN-4-OL
• Synonyms: 2-MERCAPTO-5,7-DIMETHYL-PYRIDO[2,3-D]PYRIMIDIN-4-OL;5,7-DIMETHYL-4-HYDROXY-2-MERCAPTOPYRIDO(2,3-D)-PYRIMIDINE;2,3-Dihydro-5,7-dimethyl-2-thioxo-pyrido[2,3-d]pyrimidin-4(1H)-one
• CAS NO: 49600-56-8
• Molecular Formula: C9H9N3OS
• Molecular Weight: 207.25
• Mol File: 49600-56-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 439°Cat760mmHg
• Flash Point: 219.3°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 2.56E-08mmHg at 25°C
• Refractive Index: 1.682
• CAS DataBase Reference: 2-MERCAPTO-5,7-DIMETHYL-PYRIDO[2,3-D]PYRIMIDIN-4-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MERCAPTO-5,7-DIMETHYL-PYRIDO[2,3-D]PYRIMIDIN-4-OL(49600-56-8)
• EPA Substance Registry System: 2-MERCAPTO-5,7-DIMETHYL-PYRIDO[2,3-D]PYRIMIDIN-4-OL(49600-56-8)

Safety Data

• Hazardous Substances Data: 49600-56-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 3449, 1958 DOI: 10.1021/ja01546a061

InChI:InChI=1/C9H9N3OS/c1-4-3-5(2)10-7-6(4)8(13)12-9(14)11-7/h3H,1-2H3,(H2,10,11,12,13,14)

Upstream product

• 1004-40-6 6-Amino-2-thiouracil 
• 123-54-6 acetylacetone 
• 86119-84-8 phosphoric acid 
• 51076-39-2 2-Amino-4,6-dimethyl-3-pyridincarbonsaeure-ethylester 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 1913-72-0 5,7-dimethyl-3H-pyrido[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Design, synthesis, and evaluation of the anticonvulsant and antidepressant activities of pyrido[2,3-d]pyrimidine derivatives

A series of pyrido[2,3-d]pyrimidine derivatives (4a–4n, 5a–5n, 6, and 7) were designed and synthesized as potential anticonvulsants and antidepressants. Their pharmacological activities were evaluated by maximal electroshock test, forced swimming test, an

SYNTHESIS AND PROPERTIES OF 2-AMINO-4,6-DIMETHYLNICOTINIC ACID ARYLAMIDES

It is shown that on boiling 2-amino-4,6-dimethylnicotinic acid arylamides with triethyl orthoformate in acetic anhydride, derivatives of 3-aryl-5,7-dimethyl-4-oxo-3,4-dihydropyridopyrimidine are formed.The same compounds are obtained by ternary condensation of ethyl 2-amino-4,6-dimethylnicotinate with triethyl orthoformate and arylamines.On reaction with urea or ammonium thiocyanate, the ethyl ester or anilides of 2-amino-4,6-dimethylnicothinic acid are converted to 2,4-dioxo- or 4-oxo-2-thio-pyridopyrimidines respectively.