4953-10-0

Basic information

• Product Name: 1-(4-methoxyphenyl)-1H-benzo[d][1,2,3]triazole
• Synonyms: 1-(4-methoxyphenyl)-1H-benzo[d][1,2,3]triazole
• CAS NO: 4953-10-0
• Molecular Weight: 225.25
• Mol File: 4953-10-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxyphenyl)-1H-benzo[d][1,2,3]triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxyphenyl)-1H-benzo[d][1,2,3]triazole(4953-10-0)
• EPA Substance Registry System: 1-(4-methoxyphenyl)-1H-benzo[d][1,2,3]triazole(4953-10-0)

Safety Data

• Hazardous Substances Data: 4953-10-0(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 100-66-3 methoxybenzene 
• 32338-02-6 2-bromo-4-methoxyaniline 
• 100-61-8 N-methylaniline 
• 18773-93-8 1-acetyl-1H-benzotriazole 
• 733-53-9 p-methoxyphenyl(phenyl)iodonium tetrafluoroborate 
• 615-43-0 2-iodophenylamine 
• 2101-87-3 p-methoxy-phenylazide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 15288-53-6 o-(trimethylsilyl)phenol 
• 88-95-9 Phthaloyl dichloride 
• 4733-52-2 phthaloyl peroxide 
• 5344-90-1 2-Aminobenzyl alcohol 
• 57601-36-2 2-(3-acetyl-3-methyltriaz-1-en-1-yl)benzoic acid 

Downstream Products

• 18992-85-3 3-methoxycarbazole 
• 1444922-98-8 C₃₁H₂₆AuN₃OP⁽¹⁺⁾*CF₃O₃S^(1-) 

Relevant articles and documents

Magnetically recoverable copper nanorods and their catalytic activity in Ullmann cross-coupling reaction

A novel polydentate ligand supported on Fe3O4@SiO2 was designed and demonstrated for the synthesis of Cu nanorods. The Fe3O4@SiO2/EP.EN.EG@Cu was characterized using X-ray diffraction, ther

Cu-catalyzed arylation of 1-acyl-1H-1,2,3-Benzotriazoles via C–N activation

An efficient copper-catalyzed arylation reaction of 1-acyl-1H-1,2,3-benzotriazoles with diaryliodonium salts via C–N activation is explored. The reaction is conducted regioselectively to form 1-aryl-1H-1,2,3-benzotriazoles in MeCN at 80 °C in the presence of cesium carbonate. 29 examples are given with the product yield of up to 84%. The probable reaction mechanism is proposed.

The Disappearing Director: The Case of Directed N-Arylation via a Removable Hydroxyl Group

A facile and broadly applicable method for the regiospecific N-arylation of benzotriazoles is reported. Copper-mediated reactions of diverse 1-hydroxy-1H-benzotriazoles with aryl boronic acids lead to 1-aryl-1H-benzotriazole 3-oxides. A N1-OH→N3 prototropy in the 1-hydroxy-1H-benzotriazoles is plausibly the underlying basis, where the tautomer is captured by the boronic acid, leading to C?N (not C?O) bond formation. Because the N?O bond in amine N-oxides and 1-hydroxy-1H-benzotriazoles can be easily reduced by diboron reagents such as (pinB)2 and B2(OH)4, exposure of the 1-aryl-1H-benzotriazole 3-oxides to B2(OH)4 then leads to facile reduction of the N?O bond resulting in diverse, regiospecifically-arylated benzotriazoles. Thus, the N-hydroxyl group in 1-hydroxy-1H-benzotriazoles acts as a disposable arylation director. (Figure presented.).