486422-59-7

Basic information

• Product Name: 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID
• Synonyms: 4-Borono-N,N-dimethylbenzenesulphonamide;4-(N,N-Dimethylsulphonamido)benzeneboronic acid 95%;{4-[(dimethylamino)sulfonyl]phenyl}boronic acid(SALTDATA: FREE);4-(DiMethylsulfaMoyl)benzeneboronic acid, 95%;[4-(diMethylsulfaMoyl)phenyl]boronic acid;Boronic acid, B-[4-[(diMethylaMino)sulfonyl]phenyl]-;4-(N,N-Dimethylsulphonamido)benzeneboronicacid95%;"(DiMethylsulfaMoyl)benzeneboronic acid, 95% "
• CAS NO: 486422-59-7
• Molecular Formula: C₈H₁₂BNO₄S
• Molecular Weight: 229.06
• EINECS: 200-528-9
• Product Categories: blocks;BoronicAcids;Sulfonamides;Boronate Ester;Boronic Acid;Potassium Trifluoroborate
• Mol File: 486422-59-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 140-144
• Boiling Point: 410°Cat760mmHg
• Flash Point: 201.7°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Keep Cold
• PKA: 7.39±0.10(Predicted)
• CAS DataBase Reference: 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID(486422-59-7)
• EPA Substance Registry System: 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID(486422-59-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 486422-59-7(Hazardous Substances Data)

Usage

General Description

4-(N,N-dimethylsulphonamido)benzenboronic acid is a boronic acid compound with a dimethylsulphonamido functional group attached to a benzene ring. It is commonly used in organic chemistry as a reagent for Suzuki-Miyaura cross-coupling reactions, a powerful tool for forming carbon-carbon bonds. 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID is highly reactive due to the presence of the boronic acid group, which can easily form covalent bonds with other organic molecules. It is also used in the synthesis of pharmaceuticals, agrochemicals, and materials science applications. Overall, 4-(N,N-dimethylsulphonamido)benzenboronic acid is a versatile and important compound in organic chemistry with a wide range of applications.

InChI:InChI=1/C8H12BNO4S/c1-10(2)15(13,14)8-5-3-7(4-6-8)9(11)12/h3-6,11-12H,1-2H3

Upstream product

• 98-58-8 4-bromobenzenesulfonyl chloride 
• 486422-04-2 N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide 
• 7732-18-5 water 

Downstream Products

• 1613712-10-9 C₂₂H₂₀ClN₃O₄S₂ 
• 1580454-46-1 C₁₄H₁₃ClN₄O₂S 
• 1580454-26-7 C₂₂H₂₃N₅O₄S₂ 
• 1354821-30-9 6-{4-[(dimethylamino)sulfonyl]phenyl}-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide 
• 1386859-76-2 ethyl 2-amino-{4-[(dimethylamino)sulfonyl]phenyl}-3H-1-benzazepine-4-carboxylate 
• 1346704-21-9 6-{4-[(dimethylamino)sulfonyl]phenyl}-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indazole-4-carboxamide 
• 1261302-40-2 C₂₆H₃₁N₅O₄S₂ 
• 915006-47-2 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid (3-cyclohex-1-enyl-4'-dimethylsulfamoyl-biphenyl-4-yl)-amide 
• 1186375-94-9 N,N-dimethyl-4-(6-oxo-5,6-dihydro-benzo[c][1,8]naphthyridin-1-yl)-benzenesulfonamide 
• 1040280-97-4 4-(3,9-diamino-8-chloro-5,6-dihydrobenzo[f]quinazolin-1-yl)-N,N-dimethylbenzenesulfonamide 
• 648905-66-2 4-{6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)-phenoxy]-naphthalen-2-yl}-N,N-dimethylbenzenesulfonamide 

Relevant articles and documents

HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF

The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i