4846-91-7

Basic information

• Product Name: Fenoxazoline
• Synonyms: FENOXAZOLINE;2-(2-Isopropylphenoxymethyl)-2-imidazoline;2-((8-ISOPROPYLNAPHTHALEN-1-YLOXY)METHYL)-4,5-DIHYDRO-1H-IMIDAZOLE (FENOXAZOLINE);4,5-Dihydro-2-[[2-(1-methylethyl)phenoxy]methyl]-1H-imidazole;Aturgyl;Nebulicina;Phenoxazoline
• CAS NO: 4846-91-7
• Molecular Formula: C₁₃H₁₈N₂O
• Molecular Weight: 218.29
• EINECS: 225-437-6
• Mol File: 4846-91-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 395 °C at 760 mmHg
• Flash Point: 192.7 °C
• Appearance: /
• Density: 1.09 g/cm³
• Vapor Pressure: 9.72E-09mmHg at 25°C
• Refractive Index: 1.6
• PKA: 9.84±0.40(Predicted)
• CAS DataBase Reference: Fenoxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: Fenoxazoline(4846-91-7)
• EPA Substance Registry System: Fenoxazoline(4846-91-7)

Safety Data

• Hazardous Substances Data: 4846-91-7(Hazardous Substances Data)

Usage

Originator

Fenoxazoline,Shanghai Lansheng

Uses

Fenoxazoline is a nasal decongestant.

Manufacturing Process

To a solution 257.5 g (1 mol) of o-isopropylphenyloxy-acetimino ether hydrochloride in 500 ml ethanol absolute were added 54 g (0.9 mol) of dry ethylene diamine. A mixture was refluxed for 3 hours. Then the mixture was cooled, filtered and concentrated in vacuo. o-Isopropylphenyloxy-methyl-2- imidazoline obtained was crystallized from acetone; M.P. 174°C; Yield 70%.

Therapeutic Function

Sympathomimetic

InChI:InChI=1/C17H20N2O/c1-12(2)14-7-3-5-13-6-4-8-15(17(13)14)20-11-16-18-9-10-19-16/h3-8,12H,9-11H2,1-2H3,(H,18,19)