484-17-3 Usage
Description
9-PHENANTHROL, also known as a metabolite of Phenanthrene, is a phenanthrol that is phenanthrene in which a hydrogen attached to a carbon in the central ring has been replaced by a hydroxy group. It is characterized by its brown powder appearance and is used in various applications due to its unique chemical properties.
Uses
Used in Chemical Research:
9-PHENANTHROL is used as a research compound for investigating C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes. This application helps in understanding the interactions and properties of these materials at a molecular level.
Used in Pharmaceutical Industry:
As a metabolite of Phenanthrene, 9-PHENANTHROL is used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Material Science:
9-PHENANTHROL, due to its brown powder form, can be used in the development of new materials or as an additive in the material science industry. Its specific properties may contribute to the enhancement of certain material characteristics, such as stability or reactivity.
Synthesis Reference(s)
The Journal of Organic Chemistry, 24, p. 86, 1959 DOI: 10.1021/jo01083a025Tetrahedron Letters, 29, p. 5459, 1988 DOI: 10.1016/S0040-4039(00)80786-8
Biochem/physiol Actions
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
Check Digit Verification of cas no
The CAS Registry Mumber 484-17-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 484-17:
(5*4)+(4*8)+(3*4)+(2*1)+(1*7)=73
73 % 10 = 3
So 484-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
484-17-3Relevant articles and documents
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Fieser,Jacobsen,Price
, p. 2163,2165 (1936)
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Itoh et al.
, p. 1059,1060-1062 (1979)
A simple Hückel model-driven strategy to overcome electronic barriers to retro-Brook silylation relevant to aryne and bisaryne precursor synthesis
Neal, Edward A.,Werling,Jones, Christopher R.
, p. 1663 - 1666 (2021/02/26)
ortho-Silylaryl triflate precursors (oSATs) have been responsible for many recent advances in aryne chemistry and are most commonly accessed from the corresponding 2-bromophenol. A retro-BrookO- toC-silyl transfer is a key step in this synthesis but not all aromatic species are amenable to the transformation, with no functionalized bisbenzyneoSATs reported. Simple Hückel models are presented which show that the calculated aromaticity at the brominated position is an accurate predictor of successful retro-Brook reaction, validated synthetically by a new success and a predicted failure. From this, the synthesis of a novel difunctionalized bisaryne precursor has been tested, requiring different approaches to install the twoC-silyl groups. The first successful use of a disubstitutedo-silylaryl sulfonate bisbenzyne precursor in Diels-Alder reactions is then shown.
ELECTROACTIVE COMPOUNDS
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Page/Page column 41-43, (2021/02/05)
There is provided a compound having Formula (I) In Formula I = Ar1 is a hydrocarbon aryl group, a heteroaryl group, or a substituted derivative thereof; and Q has Formula (Q1), (Q2), or (Q3) The variables are described in detail herein.
