482-28-0 Usage
General Description
Cinchonamine is an alkaloid compound found in the bark of certain species of trees in the genus Cinchona. It is structurally related to quinine, a well-known antimalarial drug also derived from Cinchona bark. Cinchonamine has been studied for its potential pharmacological properties, including anti-inflammatory, antioxidant, and anti-cancer activities. It has also been found to exhibit antimicrobial effects against certain bacteria and fungi. Furthermore, cinchonamine has been explored for its potential use in the synthesis of other pharmaceutical compounds due to its unique chemical structure. Overall, research on cinchonamine suggests it may have potential therapeutic applications in medicine and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 482-28-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 482-28:
(5*4)+(4*8)+(3*2)+(2*2)+(1*8)=70
70 % 10 = 0
So 482-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2O/c1-2-13-12-21-9-7-14(13)11-18(21)19-16(8-10-22)15-5-3-4-6-17(15)20-19/h2-6,13-14,18,20,22H,1,7-12H2/t13-,14-,18-/m0/s1
482-28-0Relevant articles and documents
ORGANOMETALLIC REAGENTS IN SYNTHESIS A NEW PROTOCOL FOR CONSTRUCTION OF THE INDOLE NUCLEUS
Smith, III, Amos B.,Visnick, Melean,Haseltine, John N.,Sprengeler, Paul A.
, p. 2957 - 2970 (2007/10/02)
Organodilithium reagents derived from 2-alkyl-N-trimethylsilyl anilines undergo condensation with esters of carboxylic acids to afford substituted indoles.A total of 16 examples are reported; yields in general were good.In conjuction with this program, a convenient, large-scale procedure for preparation of monosilylated anilines was also developed.To demonstrate the utility of the new indole protocol in natural products synthesis, efficient syntheses of (+)-cinchonamine and (+)-epi-cinchonamine as well as a tetracyclic model system for the architecturally complex penitrem mycotoxins were completed in regio- and stereoselective fashion.
