4606-15-9

Basic information

• Product Name: FEMA 2955
• Synonyms: PROPYL PHENYLACETATE;N-PROPYL PHENYLACETATE;N-PROPYL-ALPHA-TOLUATE;FEMA 2955;Acetic acid, phenyl-, propyl ester;Benzeneaceticacid,propylester;Phenylacetic acid propyl ester;phenylaceticacidpropylester
• CAS NO: 4606-15-9
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• EINECS: 225-012-5
• Mol File: 4606-15-9.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 240 °C753 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.005 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0312mmHg at 25°C
• Refractive Index: n20/D 1.492(lit.)
• CAS DataBase Reference: FEMA 2955(CAS DataBase Reference)
• NIST Chemistry Reference: FEMA 2955(4606-15-9)
• EPA Substance Registry System: FEMA 2955(4606-15-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4606-15-9(Hazardous Substances Data)

Usage

Description

FEMA 2955, also known as propyl phenylacetate, is a chemical compound with a distinctive honey-like, apricot-rose odor and a sweet, honey-like taste. It is commonly used in various industries for its unique flavor and fragrance properties.

Uses

Used in Flavor Industry:
FEMA 2955 is used as a flavoring agent for its sweet, honey-like taste. It is commonly used in food and beverage products to enhance their flavor and provide a pleasant taste experience.
Used in Fragrance Industry:
FEMA 2955 is used as a fragrance ingredient for its characteristic honey-like, apricot-rose odor. It is often incorporated into perfumes, colognes, and other scented products to create a unique and appealing aroma.
Used in Cosmetic Industry:
FEMA 2955 is used as a scent additive in cosmetic products such as lotions, creams, and body washes. Its sweet, honey-like aroma adds a pleasant scent to these products, making them more enjoyable to use.
Used in Pharmaceutical Industry:
FEMA 2955 is used as a flavoring agent in pharmaceutical products, such as cough syrups and lozenges, to mask the bitter taste of medications and make them more palatable for patients.
Overall, FEMA 2955 is a versatile compound with a wide range of applications in various industries, primarily due to its unique flavor and fragrance properties.

Preparation

By esterification of n-propanol with phenylacetic acid.

InChI:InChI=1/C11H14O2/c1-2-8-13-11(12)9-10-6-4-3-5-7-10/h3-7H,2,8-9H2,1H3

Upstream product

• 71-23-8 propan-1-ol 
• 103-82-2 phenylacetic acid 
• 102-16-9 benzyl 2-phenylacetate 
• 50707-43-2 n-propyl-p-methylphenyltriazene 
• 688-71-1 tri-n-propyl borate 
• 201230-82-2 carbon monoxide 
• 100-39-0 benzyl bromide 
• 101-41-7 benzeneacetic acid methyl ester 
• 100-44-7 benzyl chloride 
• 1134-87-8 3-benzyl-pentane-2,4-dione 
• 108-88-3 toluene 
• 27992-27-4 sodium 2-benzylidene-1-tosylhydrazin-1-ide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 1117-19-7 dipropyl malonate 

Downstream Products

• 109-60-4 1-Propyl acetate 
• 114-70-5 sodium phenylacetate 
• 1578-63-8 d'acide 2-fluoro-2-phenyl acetique 
• 360-03-2 2,2-Difluoro-2-phenylacetic acid 
• 103-82-2 phenylacetic acid 
• 55910-09-3 propyl cyclohexane acetate 

Relevant articles and documents

[Co(MeTAA)] Metalloradical Catalytic Route to Ketenes via Carbonylation of Carbene Radicals

An efficient synthetic strategy towards beta-lactams, amides, and esters involving “in situ” generation of ketenes and subsequent trapping with nucleophiles is presented. Carbonylation of carbene radical intermediates using the cheap and highly active cobalt(II) tetramethyltetraaza[14]annulene catalyst [Co(MeTAA)] provides a convenient one-pot synthetic protocol towards substituted ketenes. N-tosylhydrazones are used as carbene precursors, thereby bridging the gap between aldehydes and ketenes. Activation of these carbene precursors by the metalloradical cobalt(II) catalyst affords CoIII-carbene radicals, which subsequently react with carbon monoxide to form ketenes. In the presence of a nucleophile (imine, alcohol, or amine) in the reaction medium the ketene is immediately trapped, resulting in the desired products in a one-pot synthetic protocol. The β-lactams formed upon reaction with imines are produced in a highly trans-selective manner.

Efficient microwave-assisted esterification reaction employing methanesulfonic acid supported on alumina as catalyst

A rapid and efficient protocol assisted by microwave irradiation for the synthesis of esters using methanesulfonic acid (CH3SO3H) supported on Al2O3 (AMA) as catalyst and free of solvent is described. The products were obtained in good yields and purity, with reduced reaction time, and the process is simple and environmentally benign. Copyright

PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE

A production process for substituted phenylacetic acids or ester analogues thereof is disclosed. In this process toluene or toluene substituted with various substituents, an alcohol, an oxidant and carbon monoxide are used as raw materials to obtain compounds comprising structure of phenylacetic acid ester or analogues thereof by catalysis of the complex catalyst formed from transition metal and ligand, and such compounds are hydrolyzed to obtain various substituted phenylacetic acid based compounds. This type of compounds and their derivatives serve as important fine chemicals used widely in the industries of pharmaceuticals, pesticides, perfume and the like.