458533-66-9 Usage
Description
(1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one is a penta-dien-3-one derivative featuring two 3-methoxyphenyl groups, characterized by a conjugated ketone structure. This yellow solid substance has a molecular formula of C19H18O3 and a melting point in the range of 190-194°C. It is recognized for its potential biological activities and medicinal properties, making it a valuable compound in organic synthesis and pharmaceutical research.
Uses
Used in Organic Synthesis:
(1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one is utilized as a key intermediate in organic synthesis for the development of various chemical compounds. Its unique structure allows for versatile reactions and the creation of a wide range of products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one is employed as a starting material for the synthesis of new drugs. Its potential biological activities and medicinal properties make it a promising candidate for the development of therapeutic agents.
Used in Material Science:
Due to its structural features, (1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one may also find applications in material science. Its conjugated system and chemical properties could contribute to the development of new materials with specific properties for various applications.
Further research on (1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one's properties, reactivity, and applications is ongoing, which may lead to the discovery of additional uses across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 458533-66-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,8,5,3 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 458533-66:
(8*4)+(7*5)+(6*8)+(5*5)+(4*3)+(3*3)+(2*6)+(1*6)=179
179 % 10 = 9
So 458533-66-9 is a valid CAS Registry Number.
458533-66-9Relevant articles and documents
Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells
Di Chio, Carla,Efferth, Thomas,Ettari, Roberta,Schirmeister, Tanja,Zhou, Min,Zappalà, Maria
, (2022/01/04)
This article described the synthesis and biological investigation of a series of symmetric diarylpentanoids, characterized by a dienone moiety and by a different pattern of substitution on the two phenyl rings. The series of compounds 1a–p were tested aga
Mechanistically Inspired Route toward Hexahydro-2H-chromenes via Consecutive [4 + 2] Cycloadditions
Ashtekar, Kumar Dilip,Ding, Xinliang,Toma, Edmond,Sheng, Wei,Gholami, Hadi,Rahn, Christopher,Reed, Paul,Borhan, Babak
supporting information, p. 3976 - 3979 (2016/08/30)
Utilizing two robust C-C bond-forming reactions, the Baylis-Hillman reaction and the Diels-Alder reaction, we report a highly enantio-, regio-, and diastereoselective synthesis of hexahydro-2H-chromenes via two sequential [4 + 2] cycloadditions. These tandem and formal cycloadditions have also been performed as a "one-pot" sequence to access the corresponding heterocycles constituting up to five contiguous stereocenters in excellent yields and stereoselectivity.
Method and compounds for cancer treatment utilizing NFkB as a direct or ultimate target for small molecule inhibitors
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Page/Page column 4; sheet 2, (2008/06/13)
A method is described for cancer treatment through NFκB inhibition. NFκB is a direct or ultimate target for small molecule inhibitors. These small molecule inhibitors are aimed at suppression of NFκB directly or by indirect suppression of IKK, SFK kinases, or other upstream kinases. The present invention includes small molecule inhibitors comprising three, five, and seven carbon unsaturated spacers having one or two carbonyls, flanked by substituted aryl rings. The small molecule inhibitors can be symmetrical or unsymmetrical.
