45762-41-2 Usage
Description
4-BROMO-2-ETHYLANILINE is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. It is characterized by the presence of a bromo and an ethyl group attached to the aniline moiety, which contributes to its reactivity and potential applications in chemical synthesis.
Uses
Used in Pharmaceutical Industry:
4-BROMO-2-ETHYLANILINE is used as a synthetic intermediate for the preparation of heteroaryl (arylamino)quinazoline derivatives, which have demonstrated in vitro antitumor activity. This makes it a valuable compound in the development of new and effective cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 45762-41-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,5,7,6 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 45762-41:
(7*4)+(6*5)+(5*7)+(4*6)+(3*2)+(2*4)+(1*1)=132
132 % 10 = 2
So 45762-41-2 is a valid CAS Registry Number.
45762-41-2Relevant articles and documents
Donor-substituted distyrylpyrazines: Influence of steric congestion on UV-Vis absorption and fluorescence
Wink, Christoph,Detert, Heiner
supporting information, p. 144 - 150 (2013/03/13)
Di(p-aminostyryl)pyrazines with voluminous substituents on the nitrogen and in the adjacent positions were prepared via twofold aldol condensation. Absorption and emission spectra are influenced by increasing steric hindrance because the orbital overlap between nitrogen and π-system is modulated by voluminous groups. Strong solvatochromism of the fluorescence and huge Stokes shifts result from amplified donor-acceptor interaction in the excited state. Protonation occurs at the terminal amino groups first, followed by protonation of the central pyrazine. With increasing strength of acid, absorption and emission spectra are first shifted to the blue followed by a redshift. Copyright
