452307-58-3

Basic information

• Product Name: 2-Phenanthrenecarbonitrile, 7-methoxy-10-(4-methoxyphenyl)-5-methyl-
• CAS NO: 452307-58-3
• Molecular Formula: C24H19NO2
• Molecular Weight: 353.42
• Mol File: 452307-58-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Phenanthrenecarbonitrile, 7-methoxy-10-(4-methoxyphenyl)-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenanthrenecarbonitrile, 7-methoxy-10-(4-methoxyphenyl)-5-methyl-(452307-58-3)
• EPA Substance Registry System: 2-Phenanthrenecarbonitrile, 7-methoxy-10-(4-methoxyphenyl)-5-methyl-(452307-58-3)

Safety Data

• Hazardous Substances Data: 452307-58-3(Hazardous Substances Data)

Upstream product

• 452307-56-1 4'-methoxy-6'-methyl-2'-bromomethyl-2-(4-methoxybenzoyl)biphenyl-4-carbonitrile 
• 452307-52-7 3-(4-methoxy-2,6-dimethylphenyl)-1-(4-methoxyphenyl)propynone 
• 19447-00-8 4-methoxy-2,6-dimethylbenzylaldehyde 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 452307-55-0 4'-methoxy-2',6'-dimethyl-2-(4-methoxybenzoyl)biphenyl-4-carbonitrile 
• 452307-54-9 acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester 
• 452307-53-8 2,3-dibromo-3-(4-methoxy-2,6-dimethylphenyl)-1-(4-methoxyphenyl)propan-1-one 

Downstream Products

• 452307-63-0 1-[7-hydroxy-10-(4-hydroxyphenyl)-5-methylphenanthren-2-yl]ethanone 
• 452307-60-7 1-[7-hydroxy-10-(4-hydroxyphenyl)-5-methylphenanthren-2-yl]propan-1-one 
• 452307-44-7 1-[7-hydroxy-5-methyl-10-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-phenanthren-2-yl]-ethanone 
• 452307-42-5 1-{7-hydroxy-5-methyl-10-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-phenanthren-2-yl}-2-methyl-propan-1-one 
• 524740-44-1 7-(1-hydroxy-1-methylethyl)-4-methyl-9-[4-(2-(piperidin-1-yl)ethoxy)phenyl]phenanthren-2-ol 
• 524740-45-2 7-(1-hydroxy-1,2-dimethylpropyl)-4-methyl-9-[4-(2-(piperidin-1-yl)ethoxy)phenyl]phenanthren-2-ol 
• 452307-62-9 1-[7-methoxy-10-(4-methoxyphenyl)-5-methylphenanthren-2-yl]ethanone 

Relevant articles and documents

De novo design, synthesis, and evaluation of novel nonsteroidal phenanthrene ligands for the estrogen receptor

Although there are many estrogen receptor antagonists with improved tissue selectivity profiles compared with tamoxifen, optimal tissue selectivity has not yet been demonstrated. As such there is still a need for additional diversity and new chemical scaf