452-85-7

Basic information

• Product Name: 5-Fluoro-2-methylphenol
• Synonyms: 5-FLUORO-2-METHYLPHENOL;5-Fluoro-2-methylphenol,98%;4-fluoro-2-hydroxytoluene;5-fluoro-o-cresol;5-Fluoro-2-methylphenol 98%;5-Fluoro-o-cresol (OH=1);4-Fluoro-2-hydroxytoluene, 5-Fluoro-o-cresol;4-Fluoro-2-hydroxytoluene 5-Fluoro-2-methylphenol
• CAS NO: 452-85-7
• Molecular Formula: C₇H₇FO
• Molecular Weight: 126.13
• Product Categories: Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Fluorine Compounds;Phenols;NULL
• Mol File: 452-85-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 66°C 4mm
• Flash Point: 66°C/4mm
• Appearance: /
• Density: 1,157 g/cm3
• Vapor Pressure: 0.427mmHg at 25°C
• Refractive Index: 1.514
• Storage Temp.: 2-8°C
• PKA: 9.32±0.10(Predicted)
• BRN: 3234863
• CAS DataBase Reference: 5-Fluoro-2-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Fluoro-2-methylphenol(452-85-7)
• EPA Substance Registry System: 5-Fluoro-2-methylphenol(452-85-7)

Safety Data

• Hazard Codes: C,T,Xi,Xn
• Statements: 36/37/38-22-34-21/22
• Safety Statements: 26-36/37/39-45
• RIDADR: 3265
• HazardClass: IRRITANT, CORROSIVE
• Hazardous Substances Data: 452-85-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless transparent liquid

InChI:InChI=1/C7H7FO/c1-5-2-3-6(8)4-7(5)9/h2-4,9H,1H3

Upstream product

• 352-32-9 p-fluorotoluene 
• 452-73-3 2-chloro-4-fluorotoluene 
• 367-29-3 3-fluoro-6-methylaniline 

Downstream Products

• 929529-23-7 5-(5-fluoro-2-methylphenoxymethyl)-6-(2-methoxy-4-methoxymethoxyphenyl)-2,2,4-trimethyl-1,2-dihydroquinoline 
• 95729-22-9 1-Fluoro-3-methoxy-4-methylbenzene 
• 1394933-75-5 5-fluoro-2-methyl-4-nitrophenol 
• 26829-79-8 2,4-Dimethyl-3-hydroxyfluorbenzol 
• 1225190-20-4 tert-butyl [2-amino-5-(5-fluoro-2-methylphenoxy)phenyl]methylcarbamate 
• 1072002-25-5 3-{[6-(5-fluoro-2-methylphenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid 
• 1072003-94-1 methyl 3-{[6-(5-fluoro-2-methylphenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate 
• 1225190-21-5 [6-(5-fluoro-2-methylphenoxy)-1-methyl-1H-benzimidazol-2-yl]methanol 
• 886498-51-7 1-(bromomethyl)-4-fluoro-2-methoxybenzene 

Relevant articles and documents

Synthesis method of substituted phenol

The invention provides a synthesis method of substituted phenol. The target product substituted phenol is prepared by taking substituted benzene as an initial raw material, and the whole synthetic process is high in selectivity, high in yield, convenient to operate and high in atom economy.

1,1,1-TRIFLUORO-4-PHENYL-4-METHYL-2-(1H-PYRROLO

Compounds of Formula (IA), IB), IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.