4463-03-0

Basic information

• Product Name: Trimethylphloroglucinol
• Synonyms: 2,4,6-Mesitylenetriol;2,4,6-Trimethyl-1,3,5-benzenetriol;2,4,6-TrihydroxyMesitylene;2,4,6-TriMethyl-1,3,5-benzenetriol triMethylphloroglucinol;2,4,6-triMethylbenzene-1,3,5-triol
• CAS NO: 4463-03-0
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.1898
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 4463-03-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 184-185 °C
• Boiling Point: 327.3°Cat760mmHg
• Flash Point: 162.6°C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.611
• PKA: 10.09±0.33(Predicted)
• CAS DataBase Reference: Trimethylphloroglucinol(CAS DataBase Reference)
• NIST Chemistry Reference: Trimethylphloroglucinol(4463-03-0)
• EPA Substance Registry System: Trimethylphloroglucinol(4463-03-0)

Safety Data

• Hazardous Substances Data: 4463-03-0(Hazardous Substances Data)

Usage

Chemical Properties

Pale Orange Solid

Uses

Different sources of media describe the Uses of 4463-03-0 differently. You can refer to the following data:
1. Phloroglucinol derivative used to reduce the pain intensity of irritable bowel syndrome. Antispasmodic agent. It is also used before the hysteroscopic surgery as a means to efficaciously soften the cervix.
2. TriMethylphloroglucinol is used to reduce the pain intensity of irritable bowel syndrome,it is a kind of antispasmodic agent. It is also used before the hysteroscopic surgery as a means to efficaciously soften the cervix.

InChI:InChI=1/C9H12O3/c1-4-7(10)5(2)9(12)6(3)8(4)11/h10-12H,1-3H3

Upstream product

• 108-67-8 1,3,5-trimethyl-benzene 
• 487-70-7 2,4,6-trihydroxybenzaldehyde 
• 88-03-9 2,4,6-trihydroxytoluene 
• 108-73-6 3,5-dihydroxyphenol 
• 602-96-0 2,4,6-trinitromesitylene 
• 4380-92-1 1,3,5-trisamine-2,4,6-trimethylbenzene 
• 7732-18-5 water 
• 64-19-7 acetic acid 
• 100306-38-5 2,4,6-Trimethyl-1,3,5-benzoltriamin-trihydrochlorid 
• 64-17-5 ethanol 
• 854656-95-4 3,5-diformyl-2,4,6-trihydroxytoluene 
• 50-00-0 formaldehyd 

Downstream Products

• 84752-97-6 3,6,8,8-tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-one 
• 87510-14-3 1-azaadamantane 
• 100162-31-0 3,5-diacetoxy-2,4,6-trimethylphenyl acetate 
• 778-18-7 hexamethylcyclohexane-1,3,5-trione 

Relevant articles and documents

Cetyl alcohol mediated synthesis of CuCr2O4 spinel nanoparticles: A green catalyst for selective oxidation of aromatic C-H bonds with hydrogen peroxide

We report here cetyl alcohol-promoted synthesis of spherical CuCr2O4 spinel nanoparticles with almost uniform morphology, prepared hydrothermally. Detailed characterization of the material was carried out by XRD, XPS, ICP-AES, SEM, TEM, and TGA. XRD revealed the exclusive formation of the CuCr2O4 spinel phase and TEM showed the formation of a 20-40 nm particle size. The catalyst was highly active for selective oxidation of benzene to phenol with H2O2. The influence of reaction parameters was investigated in detail. The catalyst was found to be selective for hydroxylation of other aromatic alkanes as well. The reusability of the catalyst was tested by conducting the same experiments with the spent catalyst and it was found that the catalyst does not show any significant activity loss even after 5 reuses. The benzene conversion of 67% with 94% phenol selectivity was achieved at 75°C temperature.