443-87-8 Usage
Description
3-Fluoro-2-methylphenol is an organic compound that belongs to the class of phenols. It is characterized by the presence of a hydroxyl group (-OH) attached to a methylated phenyl ring, with a fluorine atom at the 3-position. This unique structure endows it with specific chemical and biological properties, making it a versatile molecule for various applications.
Uses
Used in Pharmaceutical Industry:
3-Fluoro-2-methylphenol is used as a key intermediate in the synthesis of indole-like derivatives with ROR-gamma-t regulating activity. These derivatives have potential applications in the prevention and treatment of ROR-gamma-t-related diseases, which include various inflammatory and autoimmune disorders.
Used in Chemical Synthesis:
Due to its unique structure, 3-Fluoro-2-methylphenol can be employed as a building block in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and selectivity in chemical reactions make it a valuable component in the development of new molecules with desired properties.
Used in Research and Development:
3-Fluoro-2-methylphenol can be utilized in academic and industrial research settings to explore its potential applications and to gain insights into its chemical behavior. It can serve as a model compound for studying the effects of fluorination and methylation on the properties of phenolic compounds, as well as for investigating the structure-activity relationships of related molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 443-87-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 443-87:
(5*4)+(4*4)+(3*3)+(2*8)+(1*7)=68
68 % 10 = 8
So 443-87-8 is a valid CAS Registry Number.
443-87-8Relevant articles and documents
Method for synthesizing 3 - halogen -2 -alkyl phenol
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Paragraph 0035-0037, (2021/11/03)
The invention discloses a synthesis method of 3 -halo -2 - alkyl phenol, and belongs to the technical field of organic synthesis. At 2, 6 - dihaloalkylbenzene is used as starting material, nucleophilic substitution with dibenzyl alcohol in the presence of an inorganic base followed Pd / C hydrodebenzylation or Grignard exchange with magnesium metal in the presence of n-butylbromide/chloride followed by air/oxygen to give 3 - halo -2 - alkylphenols. The method has the advantages of high regioselectivity, good yield, simple operation process and the like, and the product purity can reach 99.5% or more.
MONOAMINE RE-UPTAKE INHIBITORS AND METHODS RELATING THERETO
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Page/Page column 29, (2010/11/25)
Monoamine re-uptake inhibitors and more specifically serotonin and noradrenaline re-uptake inhibitors are disclosed that have utility in the treatment of disorders of the central or peripheral nervous system in both men and women. The compounds of this invention have the structure: wherein R1, R2, R3, R4, R5, R6, m, n, W, X, Y, and Z are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts, esters and solvates thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting monoamine re-uptake in a subject in need thereof.
