4382-56-3 Usage
Description
Perakine is an indole alkaloid derived from the Rauvolfia plant family, characterized by an ajmalan-type skeleton with a 17alpha-acetoxy group, a 21beta-methyl group, loss of the 1-methyl group with associated unsaturation at N(1)2C(2), and a 20alpha-formyl group in place of the 20beta-ethyl side-chain. It has been shown to be identical with the alkaloid Perakine and acts as an inhibitor of aldose reductase, making it a potent drug target for diabetes.
Uses
Used in Pharmaceutical Industry:
Perakine is used as an inhibitor of aldose reductase for the treatment of diabetes. As a potent drug target, it helps in managing and controlling the progression of the disease by inhibiting the enzyme responsible for converting glucose to sorbitol, which can lead to complications in diabetic patients.
Used in Diabetes Management:
Perakine is used as a therapeutic agent for diabetes management, specifically targeting the inhibition of aldose reductase. This action helps in reducing the risk of diabetic complications and improving the overall health of patients with diabetes.
References
Khan, Khan, Siddiqui., Pakistan 1. Sci. Ind. Res., 8, 23 (1965)
Check Digit Verification of cas no
The CAS Registry Mumber 4382-56-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,8 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4382-56:
(6*4)+(5*3)+(4*8)+(3*2)+(2*5)+(1*6)=93
93 % 10 = 3
So 4382-56-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H22N2O3/c1-10-13(9-24)12-7-16-19-21(14-5-3-4-6-15(14)22-19)8-17(23(10)16)18(12)20(21)26-11(2)25/h3-6,9-10,12-13,16-18,20H,7-8H2,1-2H3/t10-,12?,13-,16-,17-,18?,20+,21+/m0/s1
