434902-57-5

Basic information

• Product Name: bis{(2-chlorothiazol-5-yl)methyl}amine
• CAS NO: 434902-57-5
• Molecular Weight: 280.202
• Mol File: 434902-57-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: bis{(2-chlorothiazol-5-yl)methyl}amine(CAS DataBase Reference)
• NIST Chemistry Reference: bis{(2-chlorothiazol-5-yl)methyl}amine(434902-57-5)
• EPA Substance Registry System: bis{(2-chlorothiazol-5-yl)methyl}amine(434902-57-5)

Safety Data

• Hazardous Substances Data: 434902-57-5(Hazardous Substances Data)

Upstream product

• 153471-67-1 2-chloro-5-(aminomethyl)thiazole hydrochloride 
• 872165-33-8 1,3,5-tris{(2-chloro-1,3-thiazol-5-yl)methyl}-1,3,5-hexahydrotriazine 
• 105827-91-6 α-Cl-β-thiazolyl chloride 

Relevant articles and documents

Production of compounds

Provided is a method for producing a compound represented by formula (2), or a salt thereof, by reacting ammonia with formaldehyde so as to obtain a mixture that contains a compound represented by formula (8), and then mixing the obtained mixture that contains the compound represented by formula (8) with a compound represented by formula (1), or a salt thereof, in the presence of a base.

COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION

A process for preparing a thiazole compound of formula (3): wherein X1 represents a hydrogen atom or a halogen atom comprising reacting a compound of formula (1): wherein X1 is as defined above, and X2 represents a halogen atom, with ammonia and formaldehyde to obtain a hexahydrotriazine compound of formula (2): wherein X1 is as defined above, and hydrolyzing the compound of formula (2).