41897-10-3Relevant articles and documents
Copper-catalyzed hydroamination of propargyl imidates
Fricke, Patrick J.,Stasko, Jenna L.,Robbins, Dylan T.,Gardner, Alexander C.,Stash, Jacqueline,Ferraro, Mark J.,Fennie, Michael W.
, p. 4510 - 4513 (2017)
Propargyl imidates derived from aromatic and aliphatic nitriles cyclize at room temperature in high yields when treated with a catalytic amount of copper (I) iodide. This 5-exo-dig process affords dihydrooxazoles which do not aromatize under the reaction